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- W2000239919 abstract "Abstract An extract of rhizomes of Curcuma longta L. (turmeric) inhibited the desaturation of dihomo‐γ‐linolenic acid (DGLA) in the arachidonic acid (AA) producing fungus Mortierella alpina 1S‐4. The factor responsible for this phenomenon was isolated and identified as curcumin (diferuloyl methane). Mycelial DGLA levels increased about two‐fold (22.3 mg/g dry weight) with a concomitant decrease in AA levels when the fungus was cultivated with curcumin. The 50% inhibitory concentration against Δ5 desaturase was 27.2 μM. Curcumin also inhibited rat liver microsomal Δ5 and Δ6 desaturases." @default.
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- W2000239919 date "1992-07-01" @default.
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- W2000239919 title "Inhibitory effect of curcumin on fatty acid desaturation inMortierella alpina 1S-4 and rat liver microsomes" @default.
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- W2000239919 doi "https://doi.org/10.1007/bf02536132" @default.
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