FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000243542> ?p ?o ?g. }

• W2000243542 endingPage "W375" @default.
• W2000243542 startingPage "W369" @default.
• W2000243542 abstract "As an increasing number of reliable protein-protein interactions (PPIs) become available and high-throughput experimental methods provide systematic identification of PPIs, there is a growing need for fast and accurate methods for discovering homologous PPIs of a newly determined PPI. PPISearch is a web server that rapidly identifies homologous PPIs (called PPI family) and infers transferability of interacting domains and functions of a query protein pair. This server first identifies two homologous families of the query, respectively, by using BLASTP to scan an annotated PPIs database (290 137 PPIs in 576 species), which is a collection of five public databases. We determined homologous PPIs from protein pairs of homologous families when these protein pairs were in the annotated database and have significant joint sequence similarity (E < or = 10(-40)) with the query. Using these homologous PPIs across multiple species, this sever infers the conserved domain-domain pairs (Pfam and InterPro domains) and function pairs (Gene Ontology annotations). Our results demonstrate that the transferability of conserved domain-domain pairs between homologous PPIs and query pairs is 88% using 103 762 PPI queries, and the transferability of conserved function pairs is 69% based on 106 997 PPI queries. The PPISearch server should be useful for searching homologous PPIs and PPI families across multiple species. The PPISearch server is available through the website at http://gemdock.life.nctu.edu.tw/ppisearch/." @default.
• W2000243542 created "2016-06-24" @default.
• W2000243542 creator A5047494827 @default.
• W2000243542 creator A5048280831 @default.
• W2000243542 creator A5069174424 @default.
• W2000243542 creator A5088590993 @default.
• W2000243542 date "2009-05-05" @default.
• W2000243542 modified "2023-09-25" @default.
• W2000243542 title "PPISearch: a web server for searching homologous protein–protein interactions across multiple species" @default.
• W2000243542 cites W1918391659 @default.
• W2000243542 cites W1972665490 @default.
• W2000243542 cites W1978876322 @default.
• W2000243542 cites W1979107927 @default.
• W2000243542 cites W2001457899 @default.
• W2000243542 cites W2019017938 @default.
• W2000243542 cites W2026353653 @default.
• W2000243542 cites W2037442572 @default.
• W2000243542 cites W2051990160 @default.
• W2000243542 cites W2097698606 @default.
• W2000243542 cites W2103017472 @default.
• W2000243542 cites W2116423958 @default.
• W2000243542 cites W2123501554 @default.
• W2000243542 cites W2124463526 @default.
• W2000243542 cites W2125725297 @default.
• W2000243542 cites W2130687290 @default.
• W2000243542 cites W2141885858 @default.
• W2000243542 cites W2148351021 @default.
• W2000243542 cites W2158559404 @default.
• W2000243542 cites W2163485494 @default.
• W2000243542 cites W2164813401 @default.
• W2000243542 cites W4210323379 @default.
• W2000243542 cites W4252706339 @default.
• W2000243542 doi "https://doi.org/10.1093/nar/gkp309" @default.
• W2000243542 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2703927" @default.
• W2000243542 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19417070" @default.
• W2000243542 hasPublicationYear "2009" @default.
• W2000243542 type Work @default.
• W2000243542 sameAs 2000243542 @default.
• W2000243542 citedByCount "32" @default.
• W2000243542 countsByYear W20002435422012 @default.
• W2000243542 countsByYear W20002435422013 @default.
• W2000243542 countsByYear W20002435422014 @default.
• W2000243542 countsByYear W20002435422015 @default.
• W2000243542 countsByYear W20002435422016 @default.
• W2000243542 countsByYear W20002435422017 @default.
• W2000243542 countsByYear W20002435422018 @default.
• W2000243542 countsByYear W20002435422019 @default.
• W2000243542 countsByYear W20002435422023 @default.
• W2000243542 crossrefType "journal-article" @default.
• W2000243542 hasAuthorship W2000243542A5047494827 @default.
• W2000243542 hasAuthorship W2000243542A5048280831 @default.
• W2000243542 hasAuthorship W2000243542A5069174424 @default.
• W2000243542 hasAuthorship W2000243542A5088590993 @default.
• W2000243542 hasBestOaLocation W20002435421 @default.
• W2000243542 hasConcept C104317684 @default.
• W2000243542 hasConcept C110875604 @default.
• W2000243542 hasConcept C11392498 @default.
• W2000243542 hasConcept C119857082 @default.
• W2000243542 hasConcept C136764020 @default.
• W2000243542 hasConcept C140331021 @default.
• W2000243542 hasConcept C14036430 @default.
• W2000243542 hasConcept C144292202 @default.
• W2000243542 hasConcept C178180057 @default.
• W2000243542 hasConcept C202264299 @default.
• W2000243542 hasConcept C41008148 @default.
• W2000243542 hasConcept C54355233 @default.
• W2000243542 hasConcept C60644358 @default.
• W2000243542 hasConcept C61272859 @default.
• W2000243542 hasConcept C64894306 @default.
• W2000243542 hasConcept C70721500 @default.
• W2000243542 hasConcept C77088390 @default.
• W2000243542 hasConcept C86803240 @default.
• W2000243542 hasConceptScore W2000243542C104317684 @default.
• W2000243542 hasConceptScore W2000243542C110875604 @default.
• W2000243542 hasConceptScore W2000243542C11392498 @default.
• W2000243542 hasConceptScore W2000243542C119857082 @default.
• W2000243542 hasConceptScore W2000243542C136764020 @default.
• W2000243542 hasConceptScore W2000243542C140331021 @default.
• W2000243542 hasConceptScore W2000243542C14036430 @default.
• W2000243542 hasConceptScore W2000243542C144292202 @default.
• W2000243542 hasConceptScore W2000243542C178180057 @default.
• W2000243542 hasConceptScore W2000243542C202264299 @default.
• W2000243542 hasConceptScore W2000243542C41008148 @default.
• W2000243542 hasConceptScore W2000243542C54355233 @default.
• W2000243542 hasConceptScore W2000243542C60644358 @default.
• W2000243542 hasConceptScore W2000243542C61272859 @default.
• W2000243542 hasConceptScore W2000243542C64894306 @default.
• W2000243542 hasConceptScore W2000243542C70721500 @default.
• W2000243542 hasConceptScore W2000243542C77088390 @default.
• W2000243542 hasConceptScore W2000243542C86803240 @default.
• W2000243542 hasIssue "suppl_2" @default.
• W2000243542 hasLocation W20002435421 @default.
• W2000243542 hasLocation W20002435422 @default.
• W2000243542 hasLocation W20002435423 @default.
• W2000243542 hasLocation W20002435424 @default.
• W2000243542 hasOpenAccess W2000243542 @default.
• W2000243542 hasPrimaryLocation W20002435421 @default.
• W2000243542 hasRelatedWork W1579587268 @default.

• next