FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000246357> ?p ?o ?g. }

• W2000246357 endingPage "271" @default.
• W2000246357 startingPage "265" @default.
• W2000246357 abstract "This study has used the recently developed in vitro quantitative autoradiographic technique to examine the effects of olfactory bulb (OB) removal on receptor-binding sites in the deafferented piriform cortex (PC) of the rat. The γ-aminobutyric acid-benzodiazepine receptor (GABA-BZR)- and muscarinic cholinergic receptor (MChR)-binding sites in layer I of PC were localized using [3H]flunitrazepam and [3H]quinuclidinyl benzilate as ligands, respectively. From the resultant autoradiograms the optical densities were measured using a Drexel-DUMAS image analysis system. The densities of BZR and MChR-binding sites were markedly increased in the PC ipsilateral to the lesion as compared to the contralateral side in those subjects that were operated in adulthood (Postnatal Day 100, PN 100). Comparisons between the unoperated and PN 100 operated animals also showed significant increases in the deafferented PC. In the animals operated on the day of birth (PN 0) no significant differences were seen between the operated and the contralateral PC. The difference between the PN 0 deafferented PC and the unoperated controls shows a slight decrease in BZR density in the former group; however, in case of the MChR there is a slight increase on the side of the lesion. These results demonstrate that deafferentation of PC by OB removal appears to modulate both the BZR-binding sites that are coupled with the GABA-A receptor complex and the MChR-binding sites. The results also suggest the possibility of a role for these neurotransmitter receptor-binding sites in plasticity following deafferentation." @default.
• W2000246357 created "2016-06-24" @default.
• W2000246357 creator A5001627084 @default.
• W2000246357 creator A5051095836 @default.
• W2000246357 date "1989-09-01" @default.
• W2000246357 modified "2023-09-27" @default.
• W2000246357 title "Plasticity-related binding of GABA and muscarinic receptor sites in piriform cortex of rat: An autoradiographic study" @default.
• W2000246357 cites W1582702727 @default.
• W2000246357 cites W1834597793 @default.
• W2000246357 cites W1884250014 @default.
• W2000246357 cites W1970254687 @default.
• W2000246357 cites W1974718962 @default.
• W2000246357 cites W1978332185 @default.
• W2000246357 cites W1994298686 @default.
• W2000246357 cites W1994757792 @default.
• W2000246357 cites W1999133340 @default.
• W2000246357 cites W1999292360 @default.
• W2000246357 cites W2001626965 @default.
• W2000246357 cites W2003513113 @default.
• W2000246357 cites W2008196529 @default.
• W2000246357 cites W2010991750 @default.
• W2000246357 cites W2011325797 @default.
• W2000246357 cites W2014196563 @default.
• W2000246357 cites W2015941198 @default.
• W2000246357 cites W2026356373 @default.
• W2000246357 cites W2031672155 @default.
• W2000246357 cites W2036377959 @default.
• W2000246357 cites W2042109148 @default.
• W2000246357 cites W2042936373 @default.
• W2000246357 cites W2043213465 @default.
• W2000246357 cites W2048800757 @default.
• W2000246357 cites W2062457243 @default.
• W2000246357 cites W2064659680 @default.
• W2000246357 cites W2065545044 @default.
• W2000246357 cites W2069279118 @default.
• W2000246357 cites W2070862722 @default.
• W2000246357 cites W2072119885 @default.
• W2000246357 cites W2075057355 @default.
• W2000246357 cites W2077824604 @default.
• W2000246357 cites W2078949357 @default.
• W2000246357 cites W2085572128 @default.
• W2000246357 cites W2090334248 @default.
• W2000246357 cites W245761671 @default.
• W2000246357 cites W2770348358 @default.
• W2000246357 cites W3148301221 @default.
• W2000246357 doi "https://doi.org/10.1016/0014-4886(89)90129-5" @default.
• W2000246357 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2548889" @default.
• W2000246357 hasPublicationYear "1989" @default.
• W2000246357 type Work @default.
• W2000246357 sameAs 2000246357 @default.
• W2000246357 citedByCount "2" @default.
• W2000246357 crossrefType "journal-article" @default.
• W2000246357 hasAuthorship W2000246357A5001627084 @default.
• W2000246357 hasAuthorship W2000246357A5051095836 @default.
• W2000246357 hasConcept C126322002 @default.
• W2000246357 hasConcept C134018914 @default.
• W2000246357 hasConcept C142724271 @default.
• W2000246357 hasConcept C156927020 @default.
• W2000246357 hasConcept C169760540 @default.
• W2000246357 hasConcept C170493617 @default.
• W2000246357 hasConcept C185592680 @default.
• W2000246357 hasConcept C201792869 @default.
• W2000246357 hasConcept C22885893 @default.
• W2000246357 hasConcept C2776219046 @default.
• W2000246357 hasConcept C2777348757 @default.
• W2000246357 hasConcept C2780382662 @default.
• W2000246357 hasConcept C2780496858 @default.
• W2000246357 hasConcept C2781156865 @default.
• W2000246357 hasConcept C2908651707 @default.
• W2000246357 hasConcept C33789571 @default.
• W2000246357 hasConcept C529278444 @default.
• W2000246357 hasConcept C71924100 @default.
• W2000246357 hasConcept C86803240 @default.
• W2000246357 hasConceptScore W2000246357C126322002 @default.
• W2000246357 hasConceptScore W2000246357C134018914 @default.
• W2000246357 hasConceptScore W2000246357C142724271 @default.
• W2000246357 hasConceptScore W2000246357C156927020 @default.
• W2000246357 hasConceptScore W2000246357C169760540 @default.
• W2000246357 hasConceptScore W2000246357C170493617 @default.
• W2000246357 hasConceptScore W2000246357C185592680 @default.
• W2000246357 hasConceptScore W2000246357C201792869 @default.
• W2000246357 hasConceptScore W2000246357C22885893 @default.
• W2000246357 hasConceptScore W2000246357C2776219046 @default.
• W2000246357 hasConceptScore W2000246357C2777348757 @default.
• W2000246357 hasConceptScore W2000246357C2780382662 @default.
• W2000246357 hasConceptScore W2000246357C2780496858 @default.
• W2000246357 hasConceptScore W2000246357C2781156865 @default.
• W2000246357 hasConceptScore W2000246357C2908651707 @default.
• W2000246357 hasConceptScore W2000246357C33789571 @default.
• W2000246357 hasConceptScore W2000246357C529278444 @default.
• W2000246357 hasConceptScore W2000246357C71924100 @default.
• W2000246357 hasConceptScore W2000246357C86803240 @default.
• W2000246357 hasIssue "3" @default.
• W2000246357 hasLocation W20002463571 @default.
• W2000246357 hasLocation W20002463572 @default.
• W2000246357 hasOpenAccess W2000246357 @default.
• W2000246357 hasPrimaryLocation W20002463571 @default.
• W2000246357 hasRelatedWork W1938019538 @default.

• next