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• W2000246544 abstract "Patients with metastatic colorectal cancer have a poor prognosis and present a challenge to clinicians. The role of the antiepidermal growth factor receptor (EGFR) pathway in tumorogenesis and tumor progression has been well defined. This paper will review the use of anti-EGFR monoclonal antibodies in the treatment of operable, as well as metastatic colorectal cancer both in the setting of KRAS mutation unselected patients and later in KRAS wild-type patients. Active investigations designed to further identify predictive biomarkers that may be potentially druggable are reviewed as well." @default.
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• W2000246544 date "2012-10-08" @default.
• W2000246544 modified "2023-09-26" @default.
• W2000246544 title "Antiepidermal Growth Factor Receptor Monoclonal Antibodies: Applications in Colorectal Cancer" @default.
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• W2000246544 doi "https://doi.org/10.1155/2012/198197" @default.
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