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- W2000247167 abstract "The incidence of various types of hematological neoplasms varies with race. Among the lymphoid malignancies, B-cell lymphomas and leukemias predominate in most races, but not in Japanese. For instance, chronic lymphocytic leukemia (B-CLL) occurs rarely in Japanese as compared to other races. However, well-characterized T cell malignancies occur in Japanese adults, including Sezary syndrome, mycosis fungoides and adult T-cell leukemia. Adult T-cell leukemia (ATL) was proposed by Uchiyama et al. (1977), to be a new disease entity distinct from other known malignancies. Subsequently much attention has been paid to this disease in Japan, because of its characteristic neoplastic cell morphology, clinical and pathological features and the endemic distribution in south-western Japan. Hanaoka 's group characterized the cytological and histological features of ATL (Hanaoka et al., 1982). With the accumulation of pathological and clinical findings in cases of ATL and non-leukemic pleomorphic T-cell lymphoma (one type of malignant T-cell lymphoma) these two diseases were included in one category called adult T-cell leukemia/lymphoma (ATLL). However, the abbreviation ATL, not ATLL, will be used in this review article for simplicity, unless otherwise stated." @default.
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- W2000247167 date "1986-01-01" @default.
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- W2000247167 title "Molecular approach to adult t-cell leukemia" @default.
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- W2000247167 doi "https://doi.org/10.1002/hon.2900040103" @default.
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