Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000247925> ?p ?o ?g. }
- W2000247925 endingPage "490" @default.
- W2000247925 startingPage "477" @default.
- W2000247925 abstract "Radiolabeled amino acids represent a promising class of tumor imaging agents, and the determination of the optimal characteristics of these tracers remains an area of active investigation. A new (18)F-labeled branched amino acid, 2-amino-4-[(18)F]fluoro-2-methylbutanoic acid (FAMB), has been prepared in 36% decay-corrected yield using no-carrier-added [(18)F]fluoride. In vitro uptake assays with rat 9L gliosarcoma cells suggest that [(18)F]FAMB was transported primarily via the L type amino acid transport system. In vivo studies with [(18)F]FAMB demonstrated tumor to normal brain ratios of 14:1 in rats with intracranial 9L gliosarcoma tumors at 60 minutes after injection. Comparison of [(18)F]FAMB with structurally related (18)F-labeled branched amino acids demonstrated that A type transport in vitro was positively correlated with the tumor to brain ratios observed in vivo." @default.
- W2000247925 created "2016-06-24" @default.
- W2000247925 creator A5001479419 @default.
- W2000247925 creator A5034148122 @default.
- W2000247925 creator A5036023937 @default.
- W2000247925 creator A5040383472 @default.
- W2000247925 creator A5046742262 @default.
- W2000247925 creator A5053092125 @default.
- W2000247925 creator A5056507574 @default.
- W2000247925 creator A5059332651 @default.
- W2000247925 creator A5061676019 @default.
- W2000247925 creator A5084693103 @default.
- W2000247925 date "2003-05-01" @default.
- W2000247925 modified "2023-10-16" @default.
- W2000247925 title "Synthesis and evaluation of 2-amino-4-[18F]fluoro-2-methylbutanoic acid (FAMB): relationship of amino acid transport to tumor imaging properties of branched fluorinated amino acids" @default.
- W2000247925 cites W1519325153 @default.
- W2000247925 cites W1571311092 @default.
- W2000247925 cites W1963715209 @default.
- W2000247925 cites W1970345681 @default.
- W2000247925 cites W1972126694 @default.
- W2000247925 cites W1976490782 @default.
- W2000247925 cites W1994991276 @default.
- W2000247925 cites W2002786609 @default.
- W2000247925 cites W2012915480 @default.
- W2000247925 cites W2022100934 @default.
- W2000247925 cites W2022605882 @default.
- W2000247925 cites W2031849543 @default.
- W2000247925 cites W2034225567 @default.
- W2000247925 cites W2037416539 @default.
- W2000247925 cites W2049429481 @default.
- W2000247925 cites W2057875517 @default.
- W2000247925 cites W2060017835 @default.
- W2000247925 cites W2081868313 @default.
- W2000247925 cites W2087898563 @default.
- W2000247925 cites W2145806440 @default.
- W2000247925 cites W2329219736 @default.
- W2000247925 cites W2951091665 @default.
- W2000247925 cites W4248149600 @default.
- W2000247925 doi "https://doi.org/10.1016/s0969-8051(03)00025-8" @default.
- W2000247925 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12831985" @default.
- W2000247925 hasPublicationYear "2003" @default.
- W2000247925 type Work @default.
- W2000247925 sameAs 2000247925 @default.
- W2000247925 citedByCount "28" @default.
- W2000247925 countsByYear W20002479252012 @default.
- W2000247925 countsByYear W20002479252013 @default.
- W2000247925 countsByYear W20002479252015 @default.
- W2000247925 countsByYear W20002479252016 @default.
- W2000247925 countsByYear W20002479252018 @default.
- W2000247925 countsByYear W20002479252022 @default.
- W2000247925 crossrefType "journal-article" @default.
- W2000247925 hasAuthorship W2000247925A5001479419 @default.
- W2000247925 hasAuthorship W2000247925A5034148122 @default.
- W2000247925 hasAuthorship W2000247925A5036023937 @default.
- W2000247925 hasAuthorship W2000247925A5040383472 @default.
- W2000247925 hasAuthorship W2000247925A5046742262 @default.
- W2000247925 hasAuthorship W2000247925A5053092125 @default.
- W2000247925 hasAuthorship W2000247925A5056507574 @default.
- W2000247925 hasAuthorship W2000247925A5059332651 @default.
- W2000247925 hasAuthorship W2000247925A5061676019 @default.
- W2000247925 hasAuthorship W2000247925A5084693103 @default.
- W2000247925 hasConcept C134121241 @default.
- W2000247925 hasConcept C150903083 @default.
- W2000247925 hasConcept C185592680 @default.
- W2000247925 hasConcept C191897082 @default.
- W2000247925 hasConcept C192562407 @default.
- W2000247925 hasConcept C202751555 @default.
- W2000247925 hasConcept C207001950 @default.
- W2000247925 hasConcept C2776194525 @default.
- W2000247925 hasConcept C2777295375 @default.
- W2000247925 hasConcept C502942594 @default.
- W2000247925 hasConcept C515207424 @default.
- W2000247925 hasConcept C55493867 @default.
- W2000247925 hasConcept C86803240 @default.
- W2000247925 hasConceptScore W2000247925C134121241 @default.
- W2000247925 hasConceptScore W2000247925C150903083 @default.
- W2000247925 hasConceptScore W2000247925C185592680 @default.
- W2000247925 hasConceptScore W2000247925C191897082 @default.
- W2000247925 hasConceptScore W2000247925C192562407 @default.
- W2000247925 hasConceptScore W2000247925C202751555 @default.
- W2000247925 hasConceptScore W2000247925C207001950 @default.
- W2000247925 hasConceptScore W2000247925C2776194525 @default.
- W2000247925 hasConceptScore W2000247925C2777295375 @default.
- W2000247925 hasConceptScore W2000247925C502942594 @default.
- W2000247925 hasConceptScore W2000247925C515207424 @default.
- W2000247925 hasConceptScore W2000247925C55493867 @default.
- W2000247925 hasConceptScore W2000247925C86803240 @default.
- W2000247925 hasIssue "5" @default.
- W2000247925 hasLocation W20002479251 @default.
- W2000247925 hasLocation W20002479252 @default.
- W2000247925 hasOpenAccess W2000247925 @default.
- W2000247925 hasPrimaryLocation W20002479251 @default.
- W2000247925 hasRelatedWork W1986991025 @default.
- W2000247925 hasRelatedWork W2062749443 @default.
- W2000247925 hasRelatedWork W2067512829 @default.
- W2000247925 hasRelatedWork W2086742473 @default.
- W2000247925 hasRelatedWork W2401463829 @default.
- W2000247925 hasRelatedWork W2949184651 @default.