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- W2000249591 abstract "Here, we present an approach for identifying brainstem dopaminergic pathways using resting state functional MRI. In a group of healthy individuals, we searched for significant functional connectivity between dopamine-rich midbrain areas (substantia nigra; ventral tegmental area) and a striatal region (caudate) that was modulated by both a pharmacological challenge (the administration of the dopaminergic agonist bromocriptine) and a dopamine-sensitive cognitive trait (an individual's working memory capacity). A significant inverted-U shaped connectivity pattern was found in a subset of midbrain-striatal connections, demonstrating that resting state fMRI data is sufficiently powerful to identify brainstem neuromodulatory brain networks." @default.
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- W2000249591 date "2014-01-31" @default.
- W2000249591 modified "2023-10-14" @default.
- W2000249591 title "An Approach for Identifying Brainstem Dopaminergic Pathways Using Resting State Functional MRI" @default.
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- W2000249591 doi "https://doi.org/10.1371/journal.pone.0087109" @default.
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