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- W2000262322 abstract "The effects of Panax ginseng ethanol extract and its water (WSF)-and lipid-soluble (LSF) fractions on the scopolamine-induced disruption of radial maze performance in rats were examined. Ginseng root was refluxed with ethanol, and WSF and LSF were prepared from this ethanol extract. Scopolamine (0.075-0.3mg/kg, i.p.) dose-dependently impaired the maze performance. However, the oral administration of Panax ginseng ethanol extract and WSF (2-8g dried root/kg) 90min before testing improved the maze performance disrupted by scopolamine (0.3mg/kg) in a dose-dependent manner, but LSF failed to attenuate the disruption. These data suggest that ginseng extract possesses a beneficial effect regarding spatial cognitive impairment and that the water-soluble fraction of ginseng extract mainly contributes to the effect of the ethanol extract." @default.
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- W2000262322 date "1995-01-01" @default.
- W2000262322 modified "2023-09-27" @default.
- W2000262322 title "Panax ginseng Extract Improves the Scopolamine-Induced Disruption of 8-Arm Radial Maze Performance in Rats." @default.
- W2000262322 doi "https://doi.org/10.1248/bpb.18.1439" @default.
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