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- W2000267913 abstract "A series of potent specific HIV-1 RT inhibitory compounds is described. The compounds are urea analogs of PETT (PhenylEthylThiazoleThiourea) derivatives and the series includes derivatives with an ethyl linker (1-6) and conformationally restricted analogs (7-13). The antiviral activity is determined both at the RT level and in cell culture on both native and mutant forms of HIV-1. Many compounds display activity in the nM range against wt-RT." @default.
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- W2000267913 date "1998-06-01" @default.
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- W2000267913 title "Synthesis and anti-HIV activities of urea-pETT analogs belonging to a new class of potent non-nucleoside HIV-1 Reverse transcriptase inhibitors" @default.
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- W2000267913 doi "https://doi.org/10.1016/s0960-894x(98)00249-2" @default.
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