FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000268054> ?p ?o ?g. }

• W2000268054 endingPage "E8" @default.
• W2000268054 startingPage "E3" @default.
• W2000268054 abstract "Nifedipine is a potent coronary vasodilator in the resting state and an effective afterload-reducing agent. This study was undertaken because of the concern that the addition of nifedipine to beta-blocker therapy could produce serious untoward hemodynamic consequences. Although this combination is usually well tolerated, occasional reports suggest that the combination of nifedipine and beta-blocking agents may increase the likelihood of congestive heart failure, severe hypotension or exacerbation of angina. Further, there is a need to know if the addition of nifedipine to therapy with maximally tolerated doses of long-acting nitrates and beta blockers would provide further symptomatic relief without excessive adverse effects. Finally, the effect of adjunctive nifedipine on global left ventricular performance at rest and during exercise was examined. Sixteen patients, all of whom had 3 or more episodes per week of angina pectoris despite therapy with long-acting nitrates and beta blockers, were selected. Radionuclide ventriculography was performed at rest and during exercise; global ejection fractions (EFs) were determined by manually tracing the left ventricular end-diastolic perimeter with an electronic cursor. In the first phase, beta blockers and nitrates were used; in the second phase nifedipine, 10 mg every 6 hours, was added and titrated to reduce systolic blood pressure at rest by at least 10 mm Hg or until intolerable adverse effects occurred. When nifedipine was added to therapy, the difference between global EF at rest and during exercise was reduced from - 0.15 to + 0.02 (p less than 0.00001); exercise duration was increased from 431 seconds to 532 (p less than 0.001), with only 8 patients limited by angina, compared with 16 during the initial therapy.(ABSTRACT TRUNCATED AT 250 WORDS)" @default.
• W2000268054 created "2016-06-24" @default.
• W2000268054 creator A5017004610 @default.
• W2000268054 creator A5026402995 @default.
• W2000268054 creator A5027984327 @default.
• W2000268054 creator A5044138663 @default.
• W2000268054 creator A5048262793 @default.
• W2000268054 creator A5062843291 @default.
• W2000268054 creator A5070980712 @default.
• W2000268054 date "1985-05-01" @default.
• W2000268054 modified "2023-10-16" @default.
• W2000268054 title "Addition of nifedipine to maximal beta-blocker-nitrate therapy: Effects on exercise capacity and global left ventricular performance at rest and during exercise" @default.
• W2000268054 cites W1532507708 @default.
• W2000268054 cites W1534325670 @default.
• W2000268054 cites W1965122788 @default.
• W2000268054 cites W1973398078 @default.
• W2000268054 cites W1987167095 @default.
• W2000268054 cites W1989606667 @default.
• W2000268054 cites W1990598471 @default.
• W2000268054 cites W1992344423 @default.
• W2000268054 cites W2008951902 @default.
• W2000268054 cites W2011844417 @default.
• W2000268054 cites W2018056263 @default.
• W2000268054 cites W2019650887 @default.
• W2000268054 cites W2026830049 @default.
• W2000268054 cites W2027785763 @default.
• W2000268054 cites W2041251884 @default.
• W2000268054 cites W2046429318 @default.
• W2000268054 cites W2048362620 @default.
• W2000268054 cites W2049765913 @default.
• W2000268054 cites W2050049694 @default.
• W2000268054 cites W2060577473 @default.
• W2000268054 cites W2063216876 @default.
• W2000268054 cites W2079608623 @default.
• W2000268054 cites W2079736596 @default.
• W2000268054 cites W2084562673 @default.
• W2000268054 cites W2087237000 @default.
• W2000268054 cites W2088982738 @default.
• W2000268054 cites W2089993084 @default.
• W2000268054 cites W2120714117 @default.
• W2000268054 cites W2146769003 @default.
• W2000268054 cites W2162405679 @default.
• W2000268054 doi "https://doi.org/10.1016/0002-9149(85)91204-4" @default.
• W2000268054 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3923813" @default.
• W2000268054 hasPublicationYear "1985" @default.
• W2000268054 type Work @default.
• W2000268054 sameAs 2000268054 @default.
• W2000268054 citedByCount "23" @default.
• W2000268054 crossrefType "journal-article" @default.
• W2000268054 hasAuthorship W2000268054A5017004610 @default.
• W2000268054 hasAuthorship W2000268054A5026402995 @default.
• W2000268054 hasAuthorship W2000268054A5027984327 @default.
• W2000268054 hasAuthorship W2000268054A5044138663 @default.
• W2000268054 hasAuthorship W2000268054A5048262793 @default.
• W2000268054 hasAuthorship W2000268054A5062843291 @default.
• W2000268054 hasAuthorship W2000268054A5070980712 @default.
• W2000268054 hasConcept C126322002 @default.
• W2000268054 hasConcept C164705383 @default.
• W2000268054 hasConcept C2778198053 @default.
• W2000268054 hasConcept C2778425758 @default.
• W2000268054 hasConcept C2778535784 @default.
• W2000268054 hasConcept C2779066535 @default.
• W2000268054 hasConcept C42219234 @default.
• W2000268054 hasConcept C500558357 @default.
• W2000268054 hasConcept C519063684 @default.
• W2000268054 hasConcept C71924100 @default.
• W2000268054 hasConcept C78085059 @default.
• W2000268054 hasConceptScore W2000268054C126322002 @default.
• W2000268054 hasConceptScore W2000268054C164705383 @default.
• W2000268054 hasConceptScore W2000268054C2778198053 @default.
• W2000268054 hasConceptScore W2000268054C2778425758 @default.
• W2000268054 hasConceptScore W2000268054C2778535784 @default.
• W2000268054 hasConceptScore W2000268054C2779066535 @default.
• W2000268054 hasConceptScore W2000268054C42219234 @default.
• W2000268054 hasConceptScore W2000268054C500558357 @default.
• W2000268054 hasConceptScore W2000268054C519063684 @default.
• W2000268054 hasConceptScore W2000268054C71924100 @default.
• W2000268054 hasConceptScore W2000268054C78085059 @default.
• W2000268054 hasIssue "12" @default.
• W2000268054 hasLocation W20002680541 @default.
• W2000268054 hasLocation W20002680542 @default.
• W2000268054 hasOpenAccess W2000268054 @default.
• W2000268054 hasPrimaryLocation W20002680541 @default.
• W2000268054 hasRelatedWork W2051712573 @default.
• W2000268054 hasRelatedWork W2077083067 @default.
• W2000268054 hasRelatedWork W2091139515 @default.
• W2000268054 hasRelatedWork W2355594703 @default.
• W2000268054 hasRelatedWork W2361407492 @default.
• W2000268054 hasRelatedWork W2414214185 @default.
• W2000268054 hasRelatedWork W2538662566 @default.
• W2000268054 hasRelatedWork W2965474825 @default.
• W2000268054 hasRelatedWork W3033076790 @default.
• W2000268054 hasRelatedWork W4382048704 @default.
• W2000268054 hasVolume "55" @default.
• W2000268054 isParatext "false" @default.
• W2000268054 isRetracted "false" @default.
• W2000268054 magId "2000268054" @default.
• W2000268054 workType "article" @default.