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- W2000269762 abstract "Effect of cholesterol on in vitro latex-specific IgE production by mononuclear cells from atopic dermatitis patients with latex allergy. Cholesterol enhanced latex-specific IgE production in a dose-dependent fashion, and maximal enhancement was achieved at 1 μg/ml. In contrast, cholesterol had no effect on latex -specific IgA or IgG4 production. Study for cytokine production revealed that cholesterol decreased latex-induced production of IFN-γ and IL-12, while it increased latex-induced production of IL-4, IL-10 and IL-13. These results indicate that cholesterol skews cytokine pattern toward Th2 type. Collectively, cholesterol may increase allergen-specific IgE production, which may in turn aggravate allergic symptoms." @default.
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- W2000269762 date "2005-02-01" @default.
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- W2000269762 title "Cholesterol selectively enhances in vitro latex-specific IgE production in atopic dermatitis patients with latex allergy" @default.
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- W2000269762 doi "https://doi.org/10.1016/j.lfs.2004.10.028" @default.
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