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- W200026989 abstract "Multiple system atrophy with predominant cerebellar ataxia (MSA-C) is a sporadic disorder which usually presents as a midline cerebellar disorder which progresses more rapidly than other late-onset sporadic ataxias. The patient typically becomes wheelchair-dependent within 5 years of onset. Diagnostic criteria for probable MSA-C include a sporadic, progressive adult-onset cerebellar syndrome together with additional features of parkinsonism, Babinski signs, and laryngeal stridor. Interestingly, cerebellar ataxia often improves as signs of parkinsonism emerge later in the disease. A recent consensus statement emphasizes neuroimaging features including atrophy of the putamen, middle cerebellar peduncle, or pons; FDG-PET hypometabolism in the putamen; and presynaptic nigrostriatal dopaminergic denervation with SPECT or PET imaging." @default.
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- W200026989 date "2012-01-01" @default.
- W200026989 modified "2023-09-26" @default.
- W200026989 title "Multiple System Atrophy with Cerebellar Ataxia" @default.
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- W200026989 doi "https://doi.org/10.1007/978-1-60327-426-5_106" @default.
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