FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000275719> ?p ?o ?g. }

• W2000275719 endingPage "386" @default.
• W2000275719 startingPage "381" @default.
• W2000275719 abstract "Background and aim It is still debated whether or not 123I-FP-CIT single photon emission computerized tomography (SPECT) is able to differentiate between Parkinson's disease and progressive supranuclear palsy (PSP). Our aim was to use SPECT semiquantitative analysis to assess the capacity of 123I-FP-CIT to characterize Parkinson's disease versus PSP. Patients and methods Twenty-one Parkinson's disease patients, 15 disease duration- and age-matched PSP patients and 20 age-matched healthy controls were included in this study. SPECT imaging was always performed at 4 h post-injection. The ratios of striatal (S) to non-specific occipital (O) binding for the entire striatum (S/O), caudate nuclei (C/O), putamina (P/O) were calculated in both the basal ganglia. The asymmetric index (AI) for the whole striatum was also calculated for Parkinson's disease and PSP. Results Compared to healthy controls, S/O, C/O and P/O were significantly reduced (P<0.001) both in Parkinson's disease (−46%, −43%, −49%, contralaterally to the most affected side; −41%, −37%, −41%, ipsilaterally) and in PSP (−58%, −57%, −59%, contralaterally; −58%, −57%, −59%, ipsilaterally). S/O, C/O and P/O ratio values were significantly (P<0.001) lower in PSP patients when compared to Parkinson's disease group. The asymmetric index (AI) was significantly higher (P<0.001) in Parkinson's disease than in PSP (AI: 23.6%±15.07% vs. 9.66%±5.83), but with an overlap between the two groups. Conclusion Our results confirm that 123I-FP-CIT SPECT is clinically useful for detecting nigrostriatal degeneration both in Parkinson's disease and PSP. Moreover, in our series, semiquantitative analysis using 123I-FP-CIT SPECT allowed Parkinson's disease and PSP to be discriminated because PSP patients presented a more severe and symmetric dopamine transporter loss, and the results for S/O were more accurate." @default.
• W2000275719 created "2016-06-24" @default.
• W2000275719 creator A5019371574 @default.
• W2000275719 creator A5021486254 @default.
• W2000275719 creator A5026983955 @default.
• W2000275719 creator A5033859090 @default.
• W2000275719 creator A5050533828 @default.
• W2000275719 creator A5054609820 @default.
• W2000275719 creator A5074924206 @default.
• W2000275719 date "2006-04-01" @default.
• W2000275719 modified "2023-09-25" @default.
• W2000275719 title "123I-FP-CIT in progressive supranuclear palsy and in Parkinsonʼs disease: a SPECT semiquantitative study" @default.
• W2000275719 cites W158471012 @default.
• W2000275719 cites W1994878787 @default.
• W2000275719 cites W2007346901 @default.
• W2000275719 cites W2011326830 @default.
• W2000275719 cites W2017322846 @default.
• W2000275719 cites W2029535554 @default.
• W2000275719 cites W2030802264 @default.
• W2000275719 cites W2033638327 @default.
• W2000275719 cites W2039928956 @default.
• W2000275719 cites W204017299 @default.
• W2000275719 cites W2046963670 @default.
• W2000275719 cites W2047759851 @default.
• W2000275719 cites W2051567951 @default.
• W2000275719 cites W2058691511 @default.
• W2000275719 cites W2067130491 @default.
• W2000275719 cites W2078833014 @default.
• W2000275719 cites W2086854079 @default.
• W2000275719 cites W2126130609 @default.
• W2000275719 cites W2128828473 @default.
• W2000275719 cites W2136557657 @default.
• W2000275719 cites W2149612026 @default.
• W2000275719 cites W2152044255 @default.
• W2000275719 cites W2158915008 @default.
• W2000275719 cites W2170393524 @default.
• W2000275719 doi "https://doi.org/10.1097/01.mnm.0000202858.45522.df" @default.
• W2000275719 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16531926" @default.
• W2000275719 hasPublicationYear "2006" @default.
• W2000275719 type Work @default.
• W2000275719 sameAs 2000275719 @default.
• W2000275719 citedByCount "44" @default.
• W2000275719 countsByYear W20002757192012 @default.
• W2000275719 countsByYear W20002757192013 @default.
• W2000275719 countsByYear W20002757192015 @default.
• W2000275719 countsByYear W20002757192017 @default.
• W2000275719 countsByYear W20002757192018 @default.
• W2000275719 countsByYear W20002757192019 @default.
• W2000275719 countsByYear W20002757192020 @default.
• W2000275719 countsByYear W20002757192021 @default.
• W2000275719 countsByYear W20002757192022 @default.
• W2000275719 countsByYear W20002757192023 @default.
• W2000275719 crossrefType "journal-article" @default.
• W2000275719 hasAuthorship W2000275719A5019371574 @default.
• W2000275719 hasAuthorship W2000275719A5021486254 @default.
• W2000275719 hasAuthorship W2000275719A5026983955 @default.
• W2000275719 hasAuthorship W2000275719A5033859090 @default.
• W2000275719 hasAuthorship W2000275719A5050533828 @default.
• W2000275719 hasAuthorship W2000275719A5054609820 @default.
• W2000275719 hasAuthorship W2000275719A5074924206 @default.
• W2000275719 hasConcept C126322002 @default.
• W2000275719 hasConcept C142724271 @default.
• W2000275719 hasConcept C2776477761 @default.
• W2000275719 hasConcept C2778187257 @default.
• W2000275719 hasConcept C2779134260 @default.
• W2000275719 hasConcept C2779281540 @default.
• W2000275719 hasConcept C2779734285 @default.
• W2000275719 hasConcept C2780062018 @default.
• W2000275719 hasConcept C2780441642 @default.
• W2000275719 hasConcept C2781423529 @default.
• W2000275719 hasConcept C2989005 @default.
• W2000275719 hasConcept C513476851 @default.
• W2000275719 hasConcept C529278444 @default.
• W2000275719 hasConcept C71924100 @default.
• W2000275719 hasConcept C90924648 @default.
• W2000275719 hasConceptScore W2000275719C126322002 @default.
• W2000275719 hasConceptScore W2000275719C142724271 @default.
• W2000275719 hasConceptScore W2000275719C2776477761 @default.
• W2000275719 hasConceptScore W2000275719C2778187257 @default.
• W2000275719 hasConceptScore W2000275719C2779134260 @default.
• W2000275719 hasConceptScore W2000275719C2779281540 @default.
• W2000275719 hasConceptScore W2000275719C2779734285 @default.
• W2000275719 hasConceptScore W2000275719C2780062018 @default.
• W2000275719 hasConceptScore W2000275719C2780441642 @default.
• W2000275719 hasConceptScore W2000275719C2781423529 @default.
• W2000275719 hasConceptScore W2000275719C2989005 @default.
• W2000275719 hasConceptScore W2000275719C513476851 @default.
• W2000275719 hasConceptScore W2000275719C529278444 @default.
• W2000275719 hasConceptScore W2000275719C71924100 @default.
• W2000275719 hasConceptScore W2000275719C90924648 @default.
• W2000275719 hasIssue "4" @default.
• W2000275719 hasLocation W20002757191 @default.
• W2000275719 hasLocation W20002757192 @default.
• W2000275719 hasOpenAccess W2000275719 @default.
• W2000275719 hasPrimaryLocation W20002757191 @default.
• W2000275719 hasRelatedWork W1982422745 @default.
• W2000275719 hasRelatedWork W1994192668 @default.
• W2000275719 hasRelatedWork W2000275719 @default.

• next