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- W2000276695 abstract "The embryotoxic potential of a Prudhoe Bay crude oil (PBCO) was investigated in rats. PBCO was administered orally to pregnant rats as (i) a single dose on various gestation days, (ii) a single variable dose on gestation day 6, or (iii) as daily doses from day 6 to day 17 of pregnancy. PBCO administered during the earlier stages of pregnancy (day 3, 6 or 11) but not during the later stages, affected the reproductive performance of pregnant rats by significantly increasing the number of resorptions including fetal death and by decreasing the fetal weight. A dose-dependent increase in fetomortality was also observed. Multiple exposure to low levels of crude oil also caused a significant reduction in maternal body weight besides other embryotoxic changes." @default.
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- W2000276695 date "1987-09-01" @default.
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- W2000276695 title "Embryotoxic evaluation of a prudhoe bay crude oil in rats" @default.
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- W2000276695 doi "https://doi.org/10.1016/0378-4274(87)90118-4" @default.
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