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- W2000282968 abstract "Fibrinogen concentration is routinely measured by several methods and the results may influence diagnostic and treatment strategies. It is therefore necessary that results are compatible and transferable between laboratories. In the present study, it is shown that commonly used immuno-nephelometric methods, a commercial variant of the Clauss clotting rate method, and the classical syneresis method, do not differ significantly using patient material, in the interval 2-12 g/l. A research ELISA method that measures intact fibrinogen is not linearly correlated to the syneresis method. The commutability of available calibrators and reference materials (including the WHO 2nd IS) was only 50-80% except for one of the calibrators for which the virtual concentration coincided with that obtained by the syneresis method." @default.
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- W2000282968 date "2003-01-17" @default.
- W2000282968 modified "2023-10-16" @default.
- W2000282968 title "Are Results of Fibrinogen Measurements Transferable?" @default.
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- W2000282968 doi "https://doi.org/10.1515/cclm.2003.122" @default.
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