FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000286622> ?p ?o ?g. }

• W2000286622 endingPage "423" @default.
• W2000286622 startingPage "421" @default.
• W2000286622 abstract "In contrast to most genomic DNA in mitotic cells, the promoter regions of some genes, such as the stress-inducible hsp70i gene that codes for a heat shock protein, remain uncompacted, a phenomenon called bookmarking. Here we show that hsp70i bookmarking is mediated by a transcription factor called HSF2, which binds this promoter in mitotic cells, recruits protein phosphatase 2A, and interacts with the CAP-G subunit of the condensin enzyme to promote efficient dephosphorylation and inactivation of condensin complexes in the vicinity, thereby preventing compaction at this site. Blocking HSF2-mediated bookmarking by HSF2 RNA interference decreases hsp70i induction and survival of stressed cells in the G 1 phase, which demonstrates the biological importance of gene bookmarking." @default.
• W2000286622 created "2016-06-24" @default.
• W2000286622 creator A5006588059 @default.
• W2000286622 creator A5006903289 @default.
• W2000286622 creator A5010212080 @default.
• W2000286622 creator A5017253442 @default.
• W2000286622 creator A5025712282 @default.
• W2000286622 creator A5037646345 @default.
• W2000286622 creator A5039308954 @default.
• W2000286622 creator A5063142526 @default.
• W2000286622 creator A5068495574 @default.
• W2000286622 date "2005-01-21" @default.
• W2000286622 modified "2023-10-16" @default.
• W2000286622 title "Mechanism of <i>hsp70i</i> Gene Bookmarking" @default.
• W2000286622 cites W1667902255 @default.
• W2000286622 cites W1951084990 @default.
• W2000286622 cites W1969300040 @default.
• W2000286622 cites W1971656831 @default.
• W2000286622 cites W1975622188 @default.
• W2000286622 cites W1981593440 @default.
• W2000286622 cites W1992021393 @default.
• W2000286622 cites W1997850825 @default.
• W2000286622 cites W2013683245 @default.
• W2000286622 cites W2015640955 @default.
• W2000286622 cites W2018704517 @default.
• W2000286622 cites W2022616695 @default.
• W2000286622 cites W2038932046 @default.
• W2000286622 cites W2038972512 @default.
• W2000286622 cites W2040571550 @default.
• W2000286622 cites W2086618705 @default.
• W2000286622 cites W2095640709 @default.
• W2000286622 cites W2119828465 @default.
• W2000286622 cites W2137819605 @default.
• W2000286622 cites W2166730435 @default.
• W2000286622 doi "https://doi.org/10.1126/science.1106478" @default.
• W2000286622 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15662014" @default.
• W2000286622 hasPublicationYear "2005" @default.
• W2000286622 type Work @default.
• W2000286622 sameAs 2000286622 @default.
• W2000286622 citedByCount "161" @default.
• W2000286622 countsByYear W20002866222012 @default.
• W2000286622 countsByYear W20002866222013 @default.
• W2000286622 countsByYear W20002866222014 @default.
• W2000286622 countsByYear W20002866222015 @default.
• W2000286622 countsByYear W20002866222016 @default.
• W2000286622 countsByYear W20002866222017 @default.
• W2000286622 countsByYear W20002866222018 @default.
• W2000286622 countsByYear W20002866222019 @default.
• W2000286622 countsByYear W20002866222020 @default.
• W2000286622 countsByYear W20002866222021 @default.
• W2000286622 countsByYear W20002866222022 @default.
• W2000286622 countsByYear W20002866222023 @default.
• W2000286622 crossrefType "journal-article" @default.
• W2000286622 hasAuthorship W2000286622A5006588059 @default.
• W2000286622 hasAuthorship W2000286622A5006903289 @default.
• W2000286622 hasAuthorship W2000286622A5010212080 @default.
• W2000286622 hasAuthorship W2000286622A5017253442 @default.
• W2000286622 hasAuthorship W2000286622A5025712282 @default.
• W2000286622 hasAuthorship W2000286622A5037646345 @default.
• W2000286622 hasAuthorship W2000286622A5039308954 @default.
• W2000286622 hasAuthorship W2000286622A5063142526 @default.
• W2000286622 hasAuthorship W2000286622A5068495574 @default.
• W2000286622 hasConcept C104317684 @default.
• W2000286622 hasConcept C153911025 @default.
• W2000286622 hasConcept C166703698 @default.
• W2000286622 hasConcept C176504155 @default.
• W2000286622 hasConcept C54355233 @default.
• W2000286622 hasConcept C67705224 @default.
• W2000286622 hasConcept C86803240 @default.
• W2000286622 hasConcept C93304396 @default.
• W2000286622 hasConcept C95444343 @default.
• W2000286622 hasConceptScore W2000286622C104317684 @default.
• W2000286622 hasConceptScore W2000286622C153911025 @default.
• W2000286622 hasConceptScore W2000286622C166703698 @default.
• W2000286622 hasConceptScore W2000286622C176504155 @default.
• W2000286622 hasConceptScore W2000286622C54355233 @default.
• W2000286622 hasConceptScore W2000286622C67705224 @default.
• W2000286622 hasConceptScore W2000286622C86803240 @default.
• W2000286622 hasConceptScore W2000286622C93304396 @default.
• W2000286622 hasConceptScore W2000286622C95444343 @default.
• W2000286622 hasIssue "5708" @default.
• W2000286622 hasLocation W20002866221 @default.
• W2000286622 hasLocation W20002866222 @default.
• W2000286622 hasOpenAccess W2000286622 @default.
• W2000286622 hasPrimaryLocation W20002866221 @default.
• W2000286622 hasRelatedWork W1508683831 @default.
• W2000286622 hasRelatedWork W1964957699 @default.
• W2000286622 hasRelatedWork W2066393948 @default.
• W2000286622 hasRelatedWork W2139846889 @default.
• W2000286622 hasRelatedWork W2735983404 @default.
• W2000286622 hasRelatedWork W2995222778 @default.
• W2000286622 hasRelatedWork W4252751414 @default.
• W2000286622 hasRelatedWork W4281705750 @default.
• W2000286622 hasRelatedWork W4318167744 @default.
• W2000286622 hasRelatedWork W2112242382 @default.
• W2000286622 hasVolume "307" @default.
• W2000286622 isParatext "false" @default.
• W2000286622 isRetracted "false" @default.

• next