FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000287504> ?p ?o ?g. }

• W2000287504 endingPage "109" @default.
• W2000287504 startingPage "103" @default.
• W2000287504 abstract "The effects of ipsapirone, a ligand of the 5-HT1A receptors and a new potential anxiolytic, on sleep/wakefulness regulation were examined in the rat. Injected i.p. at 1, 3 and 5 mg kg-1, this compound induced a dose-dependent reduction of paradoxical sleep for 2 to 4 hours, followed, at a dose of 5 mg kg-1, by a secondary rebound. The other states of vigilance were not modified, except at the latter dose where the amounts of wakefulness were enhanced initially and decreased secondarily, while those of SWS were enhanced from 2 to 4 hours post-treatment. The effects of ipsapirone (3 mg kg-1) persisted after infusion of the neurotoxin 5,7-dihydroxytryptamine into the dorsal raphe nucleus which induced the sub-total destruction of the serotoninergic system. Thus, the action of the 5-HT1A agonist ipsapirone on sleep/wakefulness cycles probably involves the stimulation of the post-synaptic 5-HT1A receptors." @default.
• W2000287504 created "2016-06-24" @default.
• W2000287504 creator A5026049139 @default.
• W2000287504 creator A5035710638 @default.
• W2000287504 creator A5038507730 @default.
• W2000287504 creator A5061949574 @default.
• W2000287504 creator A5081105869 @default.
• W2000287504 date "1993-06-01" @default.
• W2000287504 modified "2023-10-18" @default.
• W2000287504 title "Effects of ipsapirone, a 5-HT_1Aagonist, on sleep/wakefulness cycles: probable post-synaptic action" @default.
• W2000287504 cites W1862144680 @default.
• W2000287504 cites W1966124855 @default.
• W2000287504 cites W1967429303 @default.
• W2000287504 cites W1981935827 @default.
• W2000287504 cites W1983336401 @default.
• W2000287504 cites W1984634114 @default.
• W2000287504 cites W1985759149 @default.
• W2000287504 cites W1987680642 @default.
• W2000287504 cites W1997636185 @default.
• W2000287504 cites W2003063242 @default.
• W2000287504 cites W2004279416 @default.
• W2000287504 cites W2006622413 @default.
• W2000287504 cites W2007516768 @default.
• W2000287504 cites W2011808456 @default.
• W2000287504 cites W2017826185 @default.
• W2000287504 cites W2018113827 @default.
• W2000287504 cites W2030711496 @default.
• W2000287504 cites W2031782759 @default.
• W2000287504 cites W2033260700 @default.
• W2000287504 cites W2038582232 @default.
• W2000287504 cites W2044779961 @default.
• W2000287504 cites W2054796492 @default.
• W2000287504 cites W2069394115 @default.
• W2000287504 cites W2076435979 @default.
• W2000287504 cites W2095356255 @default.
• W2000287504 cites W2151517748 @default.
• W2000287504 cites W2330788220 @default.
• W2000287504 cites W794179026 @default.
• W2000287504 doi "https://doi.org/10.1111/j.1365-2869.1993.tb00070.x" @default.
• W2000287504 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10607079" @default.
• W2000287504 hasPublicationYear "1993" @default.
• W2000287504 type Work @default.
• W2000287504 sameAs 2000287504 @default.
• W2000287504 citedByCount "56" @default.
• W2000287504 countsByYear W20002875042012 @default.
• W2000287504 countsByYear W20002875042014 @default.
• W2000287504 countsByYear W20002875042018 @default.
• W2000287504 countsByYear W20002875042023 @default.
• W2000287504 crossrefType "journal-article" @default.
• W2000287504 hasAuthorship W2000287504A5026049139 @default.
• W2000287504 hasAuthorship W2000287504A5035710638 @default.
• W2000287504 hasAuthorship W2000287504A5038507730 @default.
• W2000287504 hasAuthorship W2000287504A5061949574 @default.
• W2000287504 hasAuthorship W2000287504A5081105869 @default.
• W2000287504 hasConcept C126322002 @default.
• W2000287504 hasConcept C134018914 @default.
• W2000287504 hasConcept C15744967 @default.
• W2000287504 hasConcept C169760540 @default.
• W2000287504 hasConcept C170493617 @default.
• W2000287504 hasConcept C185592680 @default.
• W2000287504 hasConcept C24998067 @default.
• W2000287504 hasConcept C2775864247 @default.
• W2000287504 hasConcept C2777765862 @default.
• W2000287504 hasConcept C2778362415 @default.
• W2000287504 hasConcept C2778938600 @default.
• W2000287504 hasConcept C2779320081 @default.
• W2000287504 hasConcept C2781093953 @default.
• W2000287504 hasConcept C32610206 @default.
• W2000287504 hasConcept C37000724 @default.
• W2000287504 hasConcept C522805319 @default.
• W2000287504 hasConcept C53910766 @default.
• W2000287504 hasConcept C71924100 @default.
• W2000287504 hasConceptScore W2000287504C126322002 @default.
• W2000287504 hasConceptScore W2000287504C134018914 @default.
• W2000287504 hasConceptScore W2000287504C15744967 @default.
• W2000287504 hasConceptScore W2000287504C169760540 @default.
• W2000287504 hasConceptScore W2000287504C170493617 @default.
• W2000287504 hasConceptScore W2000287504C185592680 @default.
• W2000287504 hasConceptScore W2000287504C24998067 @default.
• W2000287504 hasConceptScore W2000287504C2775864247 @default.
• W2000287504 hasConceptScore W2000287504C2777765862 @default.
• W2000287504 hasConceptScore W2000287504C2778362415 @default.
• W2000287504 hasConceptScore W2000287504C2778938600 @default.
• W2000287504 hasConceptScore W2000287504C2779320081 @default.
• W2000287504 hasConceptScore W2000287504C2781093953 @default.
• W2000287504 hasConceptScore W2000287504C32610206 @default.
• W2000287504 hasConceptScore W2000287504C37000724 @default.
• W2000287504 hasConceptScore W2000287504C522805319 @default.
• W2000287504 hasConceptScore W2000287504C53910766 @default.
• W2000287504 hasConceptScore W2000287504C71924100 @default.
• W2000287504 hasIssue "2" @default.
• W2000287504 hasLocation W20002875041 @default.
• W2000287504 hasLocation W20002875042 @default.
• W2000287504 hasOpenAccess W2000287504 @default.
• W2000287504 hasPrimaryLocation W20002875041 @default.
• W2000287504 hasRelatedWork W1967007542 @default.
• W2000287504 hasRelatedWork W1973916245 @default.
• W2000287504 hasRelatedWork W1976218163 @default.

• next