FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000288274> ?p ?o ?g. }

• W2000288274 endingPage "432" @default.
• W2000288274 startingPage "429" @default.
• W2000288274 abstract "Objectives The primary objective of this study was to identify proton pump inhibitor (PPI) prescribing patterns in a population of older adults admitted to 22 Midwestern skilled long term care facilities (LTCF) with medical coverage provided by the US Medicare Part A program. The relationship between PPI prescribing patterns and specific ICD-9 diagnostic codes and symptoms management was examined. The long-term objective is appropriate PPI prescription guidance through the development of evidence- and regulation-based pharmacy formulary and policy practices, as well as practical prescribing guidance for practitioners who are supported by this pharmacy. Design An observational cohort study was conducted, using prospectively collected and de-identified prescribing and diagnostic data from a convenience sample of all Medicare A skilled nursing patients admitted between January 1, 2010, and May 31, 2011, to 22 urban, suburban, and rural Midwestern US LTCFs. Setting and Participants A common pharmacy service de-identified and aggregated PPI prescribing data and patient diagnostic information. These secondary data were analyzed for trends and patterns related to PPI use for all Medicare A patients admitted to these 22 facilities during a 17-month period in 2010 and 2011. Measurement and Results Rates of PPI use were determined and were compared with diagnostic codes. Of 1381 total admissions, 1100 patients (79.7%) were prescribed PPI. There was no appropriate diagnosis for PPI use in 718 patients (65.3%). Gastroesophageal reflux disease (GERD) tended to be the blanket diagnosis that was used most frequently for PPIs, but there was usually no follow-up or symptomatic evidence documented of active GERD. When long-term (current) use of nonsteroidal anti-inflammatory drugs (NSAIDs) (including aspirin) and/or anticoagulant therapy (warfarin) was considered as appropriate indications for 382 patients, 336 (24%) of all Medicare patients were still receiving PPIs with no relevant gastrointestinal ICD-9 diagnostic code. Total cost of PPIs prescribed from January 2010 to June 2011 was $348,414. Conclusions The examined PPI prescribing patterns show discordance between ICD-9 diagnostic code and prescribed use of PPIs in the study population. More than half (52%) of the total number of Medicare A patients were taking the medication without an indicated diagnosis. Even when NSAIDs and anticoagulant therapy were taken into consideration as valid reasons for PPI use, 24% of all patients admitted were still prescribed PPIs without a diagnosis that indicated the need for a PPI. Considering the economic cost, potential side effects, and CMS F329 regulations, which require that an LTCF resident's drug regimen be free from unnecessary medication, it is important that prescribers in LTCFs carefully consider use of PPIs in older adults in LTCFs and monitor the continued use of PPIs to prevent both the personal cost of physical side effects and drug-drug interactions, as well as the economic cost of unnecessary medication use." @default.
• W2000288274 created "2016-06-24" @default.
• W2000288274 creator A5025936767 @default.
• W2000288274 creator A5036100587 @default.
• W2000288274 creator A5037920232 @default.
• W2000288274 creator A5043455062 @default.
• W2000288274 creator A5057183502 @default.
• W2000288274 creator A5069711974 @default.
• W2000288274 creator A5075646335 @default.
• W2000288274 creator A5077762763 @default.
• W2000288274 date "2013-06-01" @default.
• W2000288274 modified "2023-10-16" @default.
• W2000288274 title "Use of Proton Pump Inhibitors With Lack of Diagnostic Indications in 22 Midwestern US Skilled Nursing Facilities" @default.
• W2000288274 cites W1605342253 @default.
• W2000288274 cites W1954517461 @default.
• W2000288274 cites W1981475803 @default.
• W2000288274 cites W1990824360 @default.
• W2000288274 cites W2010015574 @default.
• W2000288274 cites W2014727838 @default.
• W2000288274 cites W2017665239 @default.
• W2000288274 cites W2044528346 @default.
• W2000288274 cites W2044987739 @default.
• W2000288274 cites W2046189675 @default.
• W2000288274 cites W2055470905 @default.
• W2000288274 cites W2056908939 @default.
• W2000288274 cites W2063121169 @default.
• W2000288274 cites W2082485240 @default.
• W2000288274 cites W2086009722 @default.
• W2000288274 cites W2107612566 @default.
• W2000288274 cites W2110054573 @default.
• W2000288274 cites W2134722937 @default.
• W2000288274 cites W2137973850 @default.
• W2000288274 cites W2138543113 @default.
• W2000288274 cites W2147199669 @default.
• W2000288274 cites W2167359851 @default.
• W2000288274 cites W4240777872 @default.
• W2000288274 cites W2085205111 @default.
• W2000288274 doi "https://doi.org/10.1016/j.jamda.2013.01.021" @default.
• W2000288274 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23583000" @default.
• W2000288274 hasPublicationYear "2013" @default.
• W2000288274 type Work @default.
• W2000288274 sameAs 2000288274 @default.
• W2000288274 citedByCount "40" @default.
• W2000288274 countsByYear W20002882742014 @default.
• W2000288274 countsByYear W20002882742015 @default.
• W2000288274 countsByYear W20002882742016 @default.
• W2000288274 countsByYear W20002882742017 @default.
• W2000288274 countsByYear W20002882742018 @default.
• W2000288274 countsByYear W20002882742019 @default.
• W2000288274 countsByYear W20002882742020 @default.
• W2000288274 countsByYear W20002882742021 @default.
• W2000288274 countsByYear W20002882742022 @default.
• W2000288274 countsByYear W20002882742023 @default.
• W2000288274 crossrefType "journal-article" @default.
• W2000288274 hasAuthorship W2000288274A5025936767 @default.
• W2000288274 hasAuthorship W2000288274A5036100587 @default.
• W2000288274 hasAuthorship W2000288274A5037920232 @default.
• W2000288274 hasAuthorship W2000288274A5043455062 @default.
• W2000288274 hasAuthorship W2000288274A5057183502 @default.
• W2000288274 hasAuthorship W2000288274A5069711974 @default.
• W2000288274 hasAuthorship W2000288274A5075646335 @default.
• W2000288274 hasAuthorship W2000288274A5077762763 @default.
• W2000288274 hasConcept C100406419 @default.
• W2000288274 hasConcept C104863432 @default.
• W2000288274 hasConcept C126322002 @default.
• W2000288274 hasConcept C159110408 @default.
• W2000288274 hasConcept C177713679 @default.
• W2000288274 hasConcept C194828623 @default.
• W2000288274 hasConcept C201903717 @default.
• W2000288274 hasConcept C23131810 @default.
• W2000288274 hasConcept C2426938 @default.
• W2000288274 hasConcept C2780233487 @default.
• W2000288274 hasConcept C2908647359 @default.
• W2000288274 hasConcept C45827449 @default.
• W2000288274 hasConcept C512399662 @default.
• W2000288274 hasConcept C71924100 @default.
• W2000288274 hasConcept C72563966 @default.
• W2000288274 hasConcept C99454951 @default.
• W2000288274 hasConceptScore W2000288274C100406419 @default.
• W2000288274 hasConceptScore W2000288274C104863432 @default.
• W2000288274 hasConceptScore W2000288274C126322002 @default.
• W2000288274 hasConceptScore W2000288274C159110408 @default.
• W2000288274 hasConceptScore W2000288274C177713679 @default.
• W2000288274 hasConceptScore W2000288274C194828623 @default.
• W2000288274 hasConceptScore W2000288274C201903717 @default.
• W2000288274 hasConceptScore W2000288274C23131810 @default.
• W2000288274 hasConceptScore W2000288274C2426938 @default.
• W2000288274 hasConceptScore W2000288274C2780233487 @default.
• W2000288274 hasConceptScore W2000288274C2908647359 @default.
• W2000288274 hasConceptScore W2000288274C45827449 @default.
• W2000288274 hasConceptScore W2000288274C512399662 @default.
• W2000288274 hasConceptScore W2000288274C71924100 @default.
• W2000288274 hasConceptScore W2000288274C72563966 @default.
• W2000288274 hasConceptScore W2000288274C99454951 @default.
• W2000288274 hasIssue "6" @default.
• W2000288274 hasLocation W20002882741 @default.
• W2000288274 hasLocation W20002882742 @default.
• W2000288274 hasOpenAccess W2000288274 @default.

• next