FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000294217> ?p ?o ?g. }

• W2000294217 endingPage "1247" @default.
• W2000294217 startingPage "1240" @default.
• W2000294217 abstract "Abstract The axonal transport of proteins, glycoproteins, and gangliosides in sensory neurons of the sciatic nerve was examined in adult rats exposed to acrylamide via intraperitoneal injection (40 mg/kg of body weight/day for nine consecutive days). The L5 dorsal root ganglion was injected with either [35S]methionine to label proteins or [3H]glucosamine to label, more specifically, glycoproteins and gangliosides. At times ranging from 2 to 6 h later, the sciatic nerve and injected ganglion were excised and radioactivity in consecutive 5-mm segments determined. In both control and acrylamide-treated animals, outflow profiles of [35S]methionine-labeled proteins showed a well defined crest which moved down the nerve at a rate of ± 340 mm/day. Similar outflow profiles and transport rates were seen for [3H]glucosamine-labeled glycoproteins in control animals. However, in animals treated with acrylamide, the crest of transported labeled glycoprotein was severely attenuated as it moved down the nerve. This finding suggests that in acrylamide-treated animals, axonally transported glycoproteins were preferentially transferred (unloaded or exchanged against unlabeled molecules) from the transport vector to stationary axonal structures. We also examined the clearance of axonally transported glycoproteins distal to a ligature on the nerve. The observed impairment of clearance in acrylamide-treated animals relative to controls is supportive of the above hypothesis. Acrylamide may directly affect the mechanism by which axonally transported material is unloaded from the transport vector. Alternatively, the increased rate of unloading might reflect an acrylamide-induced increase in the demand for axonally transported material." @default.
• W2000294217 created "2016-06-24" @default.
• W2000294217 creator A5049052007 @default.
• W2000294217 creator A5060834868 @default.
• W2000294217 creator A5061218038 @default.
• W2000294217 creator A5072519825 @default.
• W2000294217 creator A5082877296 @default.
• W2000294217 date "1989-04-01" @default.
• W2000294217 modified "2023-09-25" @default.
• W2000294217 title "Acrylamide-Induced Increases in Deposition of Axonally Transported Glycoproteins in Rat Sciatic Nerve" @default.
• W2000294217 cites W1504930799 @default.
• W2000294217 cites W1977009797 @default.
• W2000294217 cites W1983362227 @default.
• W2000294217 cites W1988730159 @default.
• W2000294217 cites W1996163844 @default.
• W2000294217 cites W1996925573 @default.
• W2000294217 cites W2001309011 @default.
• W2000294217 cites W2009272124 @default.
• W2000294217 cites W2009365736 @default.
• W2000294217 cites W2011866553 @default.
• W2000294217 cites W2015608582 @default.
• W2000294217 cites W2017586530 @default.
• W2000294217 cites W2021450808 @default.
• W2000294217 cites W2021562732 @default.
• W2000294217 cites W2025197275 @default.
• W2000294217 cites W2030637412 @default.
• W2000294217 cites W2033937387 @default.
• W2000294217 cites W2034965700 @default.
• W2000294217 cites W2048820591 @default.
• W2000294217 cites W2064876948 @default.
• W2000294217 cites W2070776710 @default.
• W2000294217 cites W2081647980 @default.
• W2000294217 cites W2081742199 @default.
• W2000294217 cites W2082260739 @default.
• W2000294217 cites W2083160695 @default.
• W2000294217 cites W2085794642 @default.
• W2000294217 cites W2135108155 @default.
• W2000294217 cites W2153213145 @default.
• W2000294217 cites W2168132020 @default.
• W2000294217 cites W2168481176 @default.
• W2000294217 cites W2168893957 @default.
• W2000294217 doi "https://doi.org/10.1111/j.1471-4159.1989.tb01871.x" @default.
• W2000294217 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2926398" @default.
• W2000294217 hasPublicationYear "1989" @default.
• W2000294217 type Work @default.
• W2000294217 sameAs 2000294217 @default.
• W2000294217 citedByCount "21" @default.
• W2000294217 countsByYear W20002942172015 @default.
• W2000294217 countsByYear W20002942172021 @default.
• W2000294217 crossrefType "journal-article" @default.
• W2000294217 hasAuthorship W2000294217A5049052007 @default.
• W2000294217 hasAuthorship W2000294217A5060834868 @default.
• W2000294217 hasAuthorship W2000294217A5061218038 @default.
• W2000294217 hasAuthorship W2000294217A5072519825 @default.
• W2000294217 hasAuthorship W2000294217A5082877296 @default.
• W2000294217 hasConcept C105702510 @default.
• W2000294217 hasConcept C108625454 @default.
• W2000294217 hasConcept C12554922 @default.
• W2000294217 hasConcept C134018914 @default.
• W2000294217 hasConcept C166940927 @default.
• W2000294217 hasConcept C178790620 @default.
• W2000294217 hasConcept C185592680 @default.
• W2000294217 hasConcept C2779402116 @default.
• W2000294217 hasConcept C2780159080 @default.
• W2000294217 hasConcept C2781149210 @default.
• W2000294217 hasConcept C521977710 @default.
• W2000294217 hasConcept C55493867 @default.
• W2000294217 hasConcept C70192387 @default.
• W2000294217 hasConcept C86803240 @default.
• W2000294217 hasConceptScore W2000294217C105702510 @default.
• W2000294217 hasConceptScore W2000294217C108625454 @default.
• W2000294217 hasConceptScore W2000294217C12554922 @default.
• W2000294217 hasConceptScore W2000294217C134018914 @default.
• W2000294217 hasConceptScore W2000294217C166940927 @default.
• W2000294217 hasConceptScore W2000294217C178790620 @default.
• W2000294217 hasConceptScore W2000294217C185592680 @default.
• W2000294217 hasConceptScore W2000294217C2779402116 @default.
• W2000294217 hasConceptScore W2000294217C2780159080 @default.
• W2000294217 hasConceptScore W2000294217C2781149210 @default.
• W2000294217 hasConceptScore W2000294217C521977710 @default.
• W2000294217 hasConceptScore W2000294217C55493867 @default.
• W2000294217 hasConceptScore W2000294217C70192387 @default.
• W2000294217 hasConceptScore W2000294217C86803240 @default.
• W2000294217 hasIssue "4" @default.
• W2000294217 hasLocation W20002942171 @default.
• W2000294217 hasLocation W20002942172 @default.
• W2000294217 hasOpenAccess W2000294217 @default.
• W2000294217 hasPrimaryLocation W20002942171 @default.
• W2000294217 hasRelatedWork W1907823448 @default.
• W2000294217 hasRelatedWork W2000294217 @default.
• W2000294217 hasRelatedWork W2001309011 @default.
• W2000294217 hasRelatedWork W2002108185 @default.
• W2000294217 hasRelatedWork W2016848746 @default.
• W2000294217 hasRelatedWork W2026137849 @default.
• W2000294217 hasRelatedWork W2040857245 @default.
• W2000294217 hasRelatedWork W2071398253 @default.
• W2000294217 hasRelatedWork W2134831092 @default.
• W2000294217 hasRelatedWork W2417324928 @default.

• next