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• W2000295093 abstract "The understanding of the site and nature of the cortical processing deficit in human amblyopia awaits the resolution of three fundamental questions about which there is, at present, much controversy: First, is area V1 affected as the present animal models would predict, but some imaging studies argue against? Second, how extensive is the loss of extrastriate function, and does it simply follow as a consequence of an impaired V1 input? Third, does the brain imaging deficit, be it striate or extrastriate, correlate with the well-documented psychophysical loss?--a fundamental issue on which previous brain imaging studies are divided.A spatially broadband stimulus was used to determine the functional MRI responses from the different retinotopically identified visual cortical areas in a group of normal (n = 6) and a group of amblyopic (n = 11) observers. Responses were compared between the amblyopic and fellow fixing eyes of amblyopes and between the dominant and nondominant eyes of normal subjects, in central and peripheral parts of the visual field. Psychophysical acuity and contrast sensitivity was also measured and its correlation with the brain imaging deficit determined.V1 was affected in most but not all cases; the brain-imaging deficit involved extensive regions of extrastriate cortex and, at least with the stimuli used in the study, correlated with the V1 loss, suggesting a strong V1 influence; and neither the striate nor the extrastriate deficits correlated with the psychophysical contrast threshold losses at either high or low spatial frequencies.The results suggest that there are significant suprathreshold processing deficits that are not a consequence of the well-known threshold deficit. Our preoccupation over the past 30 years with the contrast detection deficit in amblyopia limited to the processing within a circumscribed part of V1 may have to be modified to include not only processing deficits for high-contrast stimuli but also the involvement of multiple extrastriate areas." @default.
• W2000295093 created "2016-06-24" @default.
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• W2000295093 date "2007-04-01" @default.
• W2000295093 modified "2023-09-29" @default.
• W2000295093 title "Cortical Deficits in Human Amblyopia: Their Regional Distribution and Their Relationship to the Contrast Detection Deficit" @default.
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• W2000295093 cites W1897459822 @default.
• W2000295093 cites W1963930878 @default.
• W2000295093 cites W1965708423 @default.
• W2000295093 cites W1971524131 @default.
• W2000295093 cites W1971855486 @default.
• W2000295093 cites W1975938737 @default.
• W2000295093 cites W1978152302 @default.
• W2000295093 cites W1983315432 @default.
• W2000295093 cites W1984069760 @default.
• W2000295093 cites W1991258631 @default.
• W2000295093 cites W1991759430 @default.
• W2000295093 cites W1995593001 @default.
• W2000295093 cites W2001889612 @default.
• W2000295093 cites W2003630833 @default.
• W2000295093 cites W2005327238 @default.
• W2000295093 cites W2009441917 @default.
• W2000295093 cites W2015151082 @default.
• W2000295093 cites W2023812395 @default.
• W2000295093 cites W2024182554 @default.
• W2000295093 cites W2028783025 @default.
• W2000295093 cites W2029683698 @default.
• W2000295093 cites W2037411834 @default.
• W2000295093 cites W2037926997 @default.
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• W2000295093 cites W2041564767 @default.
• W2000295093 cites W2045132181 @default.
• W2000295093 cites W2047469561 @default.
• W2000295093 cites W2048483930 @default.
• W2000295093 cites W2049376965 @default.
• W2000295093 cites W2050748760 @default.
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• W2000295093 cites W2072044977 @default.
• W2000295093 cites W2075048757 @default.
• W2000295093 cites W2080691617 @default.
• W2000295093 cites W2084146775 @default.
• W2000295093 cites W2085826153 @default.
• W2000295093 cites W2087376322 @default.
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• W2000295093 cites W2165709759 @default.
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• W2000295093 cites W2184338485 @default.
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• W2000295093 doi "https://doi.org/10.1167/iovs.06-1021" @default.
• W2000295093 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17389487" @default.
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