FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000295692> ?p ?o ?g. }

• W2000295692 endingPage "2508" @default.
• W2000295692 startingPage "2501" @default.
• W2000295692 abstract "The lateral hypothalamus (LH) is an important center for the integration of autonomic and limbic information and is implicated in the modulation of visceral motor and sensory pathways, including those underlying feeding and arousal behaviors. LH neurons in vitro release both ATP and GABA. The control of ATP and GABA co-transmission in LH may underlie the participation of LH in basic aspects of arousal and reinforcement. LH neurons receive cholinergic input from the pedunculopontine and laterodorsal tegmental nuclei as well as from cholinergic interneurons within the LH per se. This study presents evidence for nicotinic acetylcholine receptor (nAChR)-mediated enhancement of GABAergic, but not of purinergic, transmission despite the co-transmission of ATP and GABA at LH synapses in vitro. Facilitation of GABAergic transmission by nicotine is inhibited by antagonists of (alphabeta)*-containing nAChRs, but is unaffected by an alpha7-selective antagonist, consistent with a nAChR-mediated enhancement of GABA release mediated by non-alpha7-containing nAChRs. Activation of muscarinic ACh receptors enhances the release of ATP while concomitantly depressing GABAergic transmission. The independent modulation of ATP/GABAergic transmission may provide a new level of synaptic flexibility in which individual neurons utilize more than one neurotransmitter but retain independent control over their synaptic activity." @default.
• W2000295692 created "2016-06-24" @default.
• W2000295692 creator A5015804995 @default.
• W2000295692 creator A5035655126 @default.
• W2000295692 date "2002-11-01" @default.
• W2000295692 modified "2023-09-29" @default.
• W2000295692 title "Cholinergic Modulation of Purinergic and GABAergic Co-Transmission at In Vitro Hypothalamic Synapses" @default.
• W2000295692 cites W1488910824 @default.
• W2000295692 cites W1566487806 @default.
• W2000295692 cites W1600455132 @default.
• W2000295692 cites W1704402503 @default.
• W2000295692 cites W1902548357 @default.
• W2000295692 cites W1966755187 @default.
• W2000295692 cites W1980710373 @default.
• W2000295692 cites W1989388706 @default.
• W2000295692 cites W1991729538 @default.
• W2000295692 cites W2020764641 @default.
• W2000295692 cites W2026331058 @default.
• W2000295692 cites W2037668299 @default.
• W2000295692 cites W2039824257 @default.
• W2000295692 cites W2045122897 @default.
• W2000295692 cites W2045621697 @default.
• W2000295692 cites W2049879893 @default.
• W2000295692 cites W2055753190 @default.
• W2000295692 cites W2072154498 @default.
• W2000295692 cites W2075300430 @default.
• W2000295692 cites W2078953408 @default.
• W2000295692 cites W2082768478 @default.
• W2000295692 cites W2084719283 @default.
• W2000295692 cites W2089758153 @default.
• W2000295692 cites W2090093798 @default.
• W2000295692 cites W2090108559 @default.
• W2000295692 cites W2094491516 @default.
• W2000295692 cites W2102405317 @default.
• W2000295692 cites W2115316299 @default.
• W2000295692 cites W2133219198 @default.
• W2000295692 cites W2135895844 @default.
• W2000295692 cites W2150132984 @default.
• W2000295692 cites W2152676266 @default.
• W2000295692 cites W2172228212 @default.
• W2000295692 cites W2321454552 @default.
• W2000295692 cites W3166732914 @default.
• W2000295692 doi "https://doi.org/10.1152/jn.00352.2002" @default.
• W2000295692 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12424289" @default.
• W2000295692 hasPublicationYear "2002" @default.
• W2000295692 type Work @default.
• W2000295692 sameAs 2000295692 @default.
• W2000295692 citedByCount "42" @default.
• W2000295692 countsByYear W20002956922012 @default.
• W2000295692 countsByYear W20002956922013 @default.
• W2000295692 countsByYear W20002956922015 @default.
• W2000295692 countsByYear W20002956922016 @default.
• W2000295692 countsByYear W20002956922017 @default.
• W2000295692 countsByYear W20002956922019 @default.
• W2000295692 countsByYear W20002956922021 @default.
• W2000295692 countsByYear W20002956922022 @default.
• W2000295692 countsByYear W20002956922023 @default.
• W2000295692 crossrefType "journal-article" @default.
• W2000295692 hasAuthorship W2000295692A5015804995 @default.
• W2000295692 hasAuthorship W2000295692A5035655126 @default.
• W2000295692 hasConcept C134018914 @default.
• W2000295692 hasConcept C169760540 @default.
• W2000295692 hasConcept C170493617 @default.
• W2000295692 hasConcept C17077164 @default.
• W2000295692 hasConcept C185592680 @default.
• W2000295692 hasConcept C188987157 @default.
• W2000295692 hasConcept C200170125 @default.
• W2000295692 hasConcept C22885893 @default.
• W2000295692 hasConcept C2775910092 @default.
• W2000295692 hasConcept C2776219046 @default.
• W2000295692 hasConcept C2779177108 @default.
• W2000295692 hasConcept C529278444 @default.
• W2000295692 hasConcept C55493867 @default.
• W2000295692 hasConcept C57306754 @default.
• W2000295692 hasConcept C86803240 @default.
• W2000295692 hasConceptScore W2000295692C134018914 @default.
• W2000295692 hasConceptScore W2000295692C169760540 @default.
• W2000295692 hasConceptScore W2000295692C170493617 @default.
• W2000295692 hasConceptScore W2000295692C17077164 @default.
• W2000295692 hasConceptScore W2000295692C185592680 @default.
• W2000295692 hasConceptScore W2000295692C188987157 @default.
• W2000295692 hasConceptScore W2000295692C200170125 @default.
• W2000295692 hasConceptScore W2000295692C22885893 @default.
• W2000295692 hasConceptScore W2000295692C2775910092 @default.
• W2000295692 hasConceptScore W2000295692C2776219046 @default.
• W2000295692 hasConceptScore W2000295692C2779177108 @default.
• W2000295692 hasConceptScore W2000295692C529278444 @default.
• W2000295692 hasConceptScore W2000295692C55493867 @default.
• W2000295692 hasConceptScore W2000295692C57306754 @default.
• W2000295692 hasConceptScore W2000295692C86803240 @default.
• W2000295692 hasIssue "5" @default.
• W2000295692 hasLocation W20002956921 @default.
• W2000295692 hasLocation W20002956922 @default.
• W2000295692 hasOpenAccess W2000295692 @default.
• W2000295692 hasPrimaryLocation W20002956921 @default.
• W2000295692 hasRelatedWork W1433464383 @default.
• W2000295692 hasRelatedWork W170043564 @default.
• W2000295692 hasRelatedWork W1885050361 @default.

• next