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- W2000297089 abstract "The experimental studies upon which this communication is based were suggested by an investigation of the necrosis produced in the liver of the dog as the result of injecting hemolytic immune sera of high hemagglutinative power.1 These necrotic lesions, which are due apparently to an obstruction of the circulation by thrombi composed of fused red blood-corpuscles, vary in position and extent, according to the dose of serum administered. Small doses cause more or less isolated lesions which may occupy any portion of the lobule; large doses produce a diffuse necrosis which spares only the tissue about the larger portal spaces. The uniformity of this necrotic lesion suggested the importance of a study of the repair process which would naturally follow in animals recovering from the acute toxic effects of the injected serum. The extent of the destruction precluded complete regeneration of liver parenchyma, and if the defect was repaired by connective-tissue proliferation, the resulting histological picture wo..." @default.
- W2000297089 created "2016-06-24" @default.
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- W2000297089 date "1906-05-01" @default.
- W2000297089 modified "2023-09-26" @default.
- W2000297089 title "Experimental Cirrhosis of the Liver" @default.
- W2000297089 doi "https://doi.org/10.1097/00000441-190605000-00089" @default.
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