SemOpenAlex |

SemOpenAlex

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000298023> ?p ?o ?g. }

Showing items 1 to 100 of ±116 with 100 items per page.

W2000298023 endingPage "214" @default.
W2000298023 startingPage "206" @default.
W2000298023 abstract "Enterotoxigenic Escherichia coli (ETEC) are the main pathogens which cause pro-inflammatory responses in intestinal epithelial cells and subsequent diarrhea in pigs, leading to a reduced growth rate and increased mortality. Administration of probiotics as feed additives displayed health benefits against intestinal infections. Bacillus amyloliquefaciens SC06 (Ba) is a candidate probiotic isolated from soil and kept at China Center for Type Culture Collection. In this study, we investigated the effect of Ba on the pro-inflammatory responses induced by ETEC in IPEC-1 cells and on diarrhea in the weaned piglets. The results in vitro showed that the mRNA expression of IL-6, IL-8, TNF-α, and IL-1α in IPEC-1 cells co-cultured with ETEC was significantly increased compared to the control, however, the gene expression of these genes decreased when IPEC-1 cells were incubated 24 h with Ba prior to ETEC infection. Furthermore, the ETEC-mediated activation of ERK1/2, p38 and JNK in IPEC-1 cells was attenuated after Ba treatment. The results in vivo showed that the dietary supplementation with Ba increased daily body weight gain by 11.85% ( P <0.05) and decreased the diarrhea incidence by 79.17% compared with the control group ( P <0.01), respectively. Together, our data suggest that Ba treatment may inhibit ETEC-induced pro-inflammatory responses by suppression of MAPK signaling pathways in intestinal epithelial cells, which provides a rationale for decreased diarrhea incidence in the Ba-supplemented diet of the weaned piglets." @default.
W2000298023 created "2016-06-24" @default.
W2000298023 creator A5021281394 @default.
W2000298023 creator A5022198231 @default.
W2000298023 creator A5043137187 @default.
W2000298023 creator A5054996570 @default.
W2000298023 creator A5069227977 @default.
W2000298023 creator A5087916830 @default.
W2000298023 date "2013-12-01" @default.
W2000298023 modified "2023-09-27" @default.
W2000298023 title "Bacillus amyloliquefaciens SC06 inhibits ETEC-induced pro-inflammatory responses by suppression of MAPK signaling pathways in IPEC-1 cells and diarrhea in weaned piglets" @default.
W2000298023 cites W1486167830 @default.
W2000298023 cites W1538419280 @default.
W2000298023 cites W1891196086 @default.
W2000298023 cites W1970936381 @default.
W2000298023 cites W1974738011 @default.
W2000298023 cites W1976242411 @default.
W2000298023 cites W1995258006 @default.
W2000298023 cites W2015074127 @default.
W2000298023 cites W2015296538 @default.
W2000298023 cites W2034516137 @default.
W2000298023 cites W2037870996 @default.
W2000298023 cites W2039232870 @default.
W2000298023 cites W2048214746 @default.
W2000298023 cites W2050969183 @default.
W2000298023 cites W2060651626 @default.
W2000298023 cites W2080569825 @default.
W2000298023 cites W2103736238 @default.
W2000298023 cites W2105849202 @default.
W2000298023 cites W2108599358 @default.
W2000298023 cites W2128712834 @default.
W2000298023 cites W2130063225 @default.
W2000298023 cites W2137597973 @default.
W2000298023 cites W2138611522 @default.
W2000298023 cites W2139981177 @default.
W2000298023 cites W2145365066 @default.
W2000298023 cites W2151437990 @default.
W2000298023 cites W2169982514 @default.
W2000298023 cites W2171967025 @default.
W2000298023 doi "https://doi.org/10.1016/j.livsci.2013.09.017" @default.
W2000298023 hasPublicationYear "2013" @default.
W2000298023 type Work @default.
W2000298023 sameAs 2000298023 @default.
W2000298023 citedByCount "15" @default.
W2000298023 countsByYear W20002980232016 @default.
W2000298023 countsByYear W20002980232017 @default.
W2000298023 countsByYear W20002980232018 @default.
W2000298023 countsByYear W20002980232019 @default.
W2000298023 countsByYear W20002980232020 @default.
W2000298023 countsByYear W20002980232021 @default.
W2000298023 countsByYear W20002980232022 @default.
W2000298023 crossrefType "journal-article" @default.
W2000298023 hasAuthorship W2000298023A5021281394 @default.
W2000298023 hasAuthorship W2000298023A5022198231 @default.
W2000298023 hasAuthorship W2000298023A5043137187 @default.
W2000298023 hasAuthorship W2000298023A5054996570 @default.
W2000298023 hasAuthorship W2000298023A5069227977 @default.
W2000298023 hasAuthorship W2000298023A5087916830 @default.
W2000298023 hasConcept C100544194 @default.
W2000298023 hasConcept C104317684 @default.
W2000298023 hasConcept C126322002 @default.
W2000298023 hasConcept C203014093 @default.
W2000298023 hasConcept C2777811704 @default.
W2000298023 hasConcept C2777871010 @default.
W2000298023 hasConcept C2779802037 @default.
W2000298023 hasConcept C2780255968 @default.
W2000298023 hasConcept C523546767 @default.
W2000298023 hasConcept C54355233 @default.
W2000298023 hasConcept C547475151 @default.
W2000298023 hasConcept C55493867 @default.
W2000298023 hasConcept C57074206 @default.
W2000298023 hasConcept C62478195 @default.
W2000298023 hasConcept C66999527 @default.
W2000298023 hasConcept C71924100 @default.
W2000298023 hasConcept C86803240 @default.
W2000298023 hasConcept C89423630 @default.
W2000298023 hasConceptScore W2000298023C100544194 @default.
W2000298023 hasConceptScore W2000298023C104317684 @default.
W2000298023 hasConceptScore W2000298023C126322002 @default.
W2000298023 hasConceptScore W2000298023C203014093 @default.
W2000298023 hasConceptScore W2000298023C2777811704 @default.
W2000298023 hasConceptScore W2000298023C2777871010 @default.
W2000298023 hasConceptScore W2000298023C2779802037 @default.
W2000298023 hasConceptScore W2000298023C2780255968 @default.
W2000298023 hasConceptScore W2000298023C523546767 @default.
W2000298023 hasConceptScore W2000298023C54355233 @default.
W2000298023 hasConceptScore W2000298023C547475151 @default.
W2000298023 hasConceptScore W2000298023C55493867 @default.
W2000298023 hasConceptScore W2000298023C57074206 @default.
W2000298023 hasConceptScore W2000298023C62478195 @default.
W2000298023 hasConceptScore W2000298023C66999527 @default.
W2000298023 hasConceptScore W2000298023C71924100 @default.
W2000298023 hasConceptScore W2000298023C86803240 @default.
W2000298023 hasConceptScore W2000298023C89423630 @default.
W2000298023 hasFunder F4320336024 @default.
W2000298023 hasIssue "1-3" @default.
W2000298023 hasLocation W20002980231 @default.
W2000298023 hasOpenAccess W2000298023 @default.