FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000298129> ?p ?o ?g. }

• W2000298129 endingPage "15321" @default.
• W2000298129 startingPage "15318" @default.
• W2000298129 abstract "Menaquinone (MK, vitamin K2) is a lipid-soluble molecule that participates in the bacterial electron transport chain. In mammalian cells, MK functions as an essential vitamin for the activation of various proteins involved in blood clotting and bone metabolism. Recently, a new pathway for the biosynthesis of this cofactor was discovered in Streptomyces coelicolor A3(2) in which chorismate is converted to aminofutalosine in a reaction catalyzed by MqnA and an unidentified enzyme. Here, we reconstitute the biosynthesis of aminofutalosine and demonstrate that the missing enzyme (aminofutalosine synthase, MqnE) is a radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoic acid. This is a new reaction type in the radical SAM superfamily." @default.
• W2000298129 created "2016-06-24" @default.
• W2000298129 creator A5020048735 @default.
• W2000298129 creator A5063530297 @default.
• W2000298129 creator A5064237607 @default.
• W2000298129 creator A5065138225 @default.
• W2000298129 date "2013-10-07" @default.
• W2000298129 modified "2023-09-23" @default.
• W2000298129 title "Menaquinone Biosynthesis: Formation of Aminofutalosine Requires a Unique Radical SAM Enzyme" @default.
• W2000298129 cites W1573058404 @default.
• W2000298129 cites W1989486497 @default.
• W2000298129 cites W1991225010 @default.
• W2000298129 cites W2006777479 @default.
• W2000298129 cites W2021421899 @default.
• W2000298129 cites W2036900344 @default.
• W2000298129 cites W2047544573 @default.
• W2000298129 cites W2051242705 @default.
• W2000298129 cites W2068725665 @default.
• W2000298129 cites W2076558529 @default.
• W2000298129 cites W2090727951 @default.
• W2000298129 cites W2092995073 @default.
• W2000298129 cites W2100918802 @default.
• W2000298129 cites W2114582288 @default.
• W2000298129 cites W2114684175 @default.
• W2000298129 cites W2116331367 @default.
• W2000298129 cites W2169221210 @default.
• W2000298129 cites W2318540405 @default.
• W2000298129 cites W2329253808 @default.
• W2000298129 cites W2414517934 @default.
• W2000298129 doi "https://doi.org/10.1021/ja408594p" @default.
• W2000298129 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3855536" @default.
• W2000298129 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24083939" @default.
• W2000298129 hasPublicationYear "2013" @default.
• W2000298129 type Work @default.
• W2000298129 sameAs 2000298129 @default.
• W2000298129 citedByCount "88" @default.
• W2000298129 countsByYear W20002981292013 @default.
• W2000298129 countsByYear W20002981292014 @default.
• W2000298129 countsByYear W20002981292015 @default.
• W2000298129 countsByYear W20002981292016 @default.
• W2000298129 countsByYear W20002981292017 @default.
• W2000298129 countsByYear W20002981292018 @default.
• W2000298129 countsByYear W20002981292019 @default.
• W2000298129 countsByYear W20002981292020 @default.
• W2000298129 countsByYear W20002981292021 @default.
• W2000298129 countsByYear W20002981292022 @default.
• W2000298129 countsByYear W20002981292023 @default.
• W2000298129 crossrefType "journal-article" @default.
• W2000298129 hasAuthorship W2000298129A5020048735 @default.
• W2000298129 hasAuthorship W2000298129A5063530297 @default.
• W2000298129 hasAuthorship W2000298129A5064237607 @default.
• W2000298129 hasAuthorship W2000298129A5065138225 @default.
• W2000298129 hasBestOaLocation W20002981292 @default.
• W2000298129 hasConcept C104317684 @default.
• W2000298129 hasConcept C134651460 @default.
• W2000298129 hasConcept C143065580 @default.
• W2000298129 hasConcept C181199279 @default.
• W2000298129 hasConcept C185592680 @default.
• W2000298129 hasConcept C197957613 @default.
• W2000298129 hasConcept C2779123261 @default.
• W2000298129 hasConcept C2779920670 @default.
• W2000298129 hasConcept C2780681812 @default.
• W2000298129 hasConcept C523546767 @default.
• W2000298129 hasConcept C54355233 @default.
• W2000298129 hasConcept C553450214 @default.
• W2000298129 hasConcept C55493867 @default.
• W2000298129 hasConcept C71240020 @default.
• W2000298129 hasConcept C86803240 @default.
• W2000298129 hasConceptScore W2000298129C104317684 @default.
• W2000298129 hasConceptScore W2000298129C134651460 @default.
• W2000298129 hasConceptScore W2000298129C143065580 @default.
• W2000298129 hasConceptScore W2000298129C181199279 @default.
• W2000298129 hasConceptScore W2000298129C185592680 @default.
• W2000298129 hasConceptScore W2000298129C197957613 @default.
• W2000298129 hasConceptScore W2000298129C2779123261 @default.
• W2000298129 hasConceptScore W2000298129C2779920670 @default.
• W2000298129 hasConceptScore W2000298129C2780681812 @default.
• W2000298129 hasConceptScore W2000298129C523546767 @default.
• W2000298129 hasConceptScore W2000298129C54355233 @default.
• W2000298129 hasConceptScore W2000298129C553450214 @default.
• W2000298129 hasConceptScore W2000298129C55493867 @default.
• W2000298129 hasConceptScore W2000298129C71240020 @default.
• W2000298129 hasConceptScore W2000298129C86803240 @default.
• W2000298129 hasIssue "41" @default.
• W2000298129 hasLocation W20002981291 @default.
• W2000298129 hasLocation W20002981292 @default.
• W2000298129 hasLocation W20002981293 @default.
• W2000298129 hasLocation W20002981294 @default.
• W2000298129 hasOpenAccess W2000298129 @default.
• W2000298129 hasPrimaryLocation W20002981291 @default.
• W2000298129 hasRelatedWork W107896380 @default.
• W2000298129 hasRelatedWork W169735115 @default.
• W2000298129 hasRelatedWork W2000298129 @default.
• W2000298129 hasRelatedWork W2058543570 @default.
• W2000298129 hasRelatedWork W2080279693 @default.
• W2000298129 hasRelatedWork W2134334821 @default.
• W2000298129 hasRelatedWork W2139005859 @default.
• W2000298129 hasRelatedWork W2150843691 @default.

• next