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- W2000298403 abstract "Polygodial was found to exhibit a fungicidal activity against a food spoilage yeast, Zygosaccharomyces bailii, with the minimum fungicidal concentration (MFC) of 50 microg/mL (0.17 mM). The time-kill curve study showed that polygodial was fungicidal at any growth stage. The primary action of polygodial comes from its ability to disrupt the native membrane-associated function of integral proteins as nonionic surface active agents (surfactants) followed by a decrease in plasma membrane fluidity. The fungicidal activity of polygodial was increased 128-fold in combination with a sublethal amount (equivalent of 1/2 MFC) of anethole and vice versa relative to the fungicidal activity of anethole. The fungicidal activity of sorbic acid was enhanced 512-fold in combination with 1/2 MFC of polygodial. Conversely, the fungicidal activity of polygodial was enhanced 128-fold in combination with 1/2 MFC of sorbic acid." @default.
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- W2000298403 date "2005-06-01" @default.
- W2000298403 modified "2023-10-06" @default.
- W2000298403 title "Naturally Occurring Antifungal Agents against <i>Zygosaccharomyces bailii</i> and Their Synergism" @default.
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- W2000298403 doi "https://doi.org/10.1021/jf0500987" @default.
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