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- W2000299976 abstract "<h4>ABSTRACT</h4> <p>A surgical technique is described combining submacular anti-vascular endothelial growth factor (anti-VEGF) and recombinant tissue plasminogen activator (r-TPA) with pneumatic displacement of massive submacular hemorrhage in age-related macular degeneration. An 84-year-old man with a large, acute submacular hemorrhage secondary to age-related macular degeneration underwent combination vitrectomy, submacular anti-VEGF and r-TPA injection with pneumatic displacement of the hemorrhage. At the last follow-up visit, 7 months after surgery, visual acuity was 20/80 with a small fibrovascular pigment epithelial detachment and atrophic retinal pigment epithelial changes. A 77-year-old woman with known age-related macular degeneration underwent a similar surgical procedure for a similar acute, large submacular hemorrhage related to age-related macular degeneration. Nine months after surgery, the visual acuity was 20/70<sup>-1</sup>. Combination submacular anti-VEGF therapy delivered at the time of pars plana vitrectomy and submacular tissue plasminogen activator assisted hemorrhage displacement may be a viable treatment strategy for the management massive submacular hemorrhage. [<cite>Ophthalmic Surg Lasers Imaging</cite> 2009;40:308-315.]</p> <h4> </h4>" @default.
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- W2000299976 date "2009-01-01" @default.
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- W2000299976 title "Submacular Combination Treatment for Management of Acute, Massive Submacular Hemorrhage in Age-Related Macular Degeneration" @default.
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- W2000299976 doi "https://doi.org/10.3928/15428877-20090430-16" @default.
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