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- W2000304827 endingPage "82" @default.
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- W2000304827 abstract "Uncovering the functions of thousands of gene products, in various states of post-translational modification, is a key challenge in the post-genome era. To identify small-molecule probes for each protein function, high-throughput methods for ligand discovery are needed. In recent years, small-molecule microarrays (SMMs) have emerged as high-throughput and miniaturized screening tools for discovering protein–small-molecule interactions. Microarrays of small molecules from a variety of sources, including FDA-approved drugs, natural products and products of combinatorial chemistry and diversity-oriented synthesis, have been prepared and screened by several laboratories, leading to several newly discovered protein–ligand pairs." @default.
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- W2000304827 date "2007-02-01" @default.
- W2000304827 modified "2023-09-26" @default.
- W2000304827 title "A pipeline for ligand discovery using small-molecule microarrays" @default.
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- W2000304827 doi "https://doi.org/10.1016/j.cbpa.2006.11.031" @default.
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