Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000306719> ?p ?o ?g. }
- W2000306719 endingPage "116" @default.
- W2000306719 startingPage "105" @default.
- W2000306719 abstract "Nk(x)-type homeobox genes are an evolutionarily conserved family that regulate diverse developmental processes. Here we describe a novel Drosophila gene, Nk6, which encodes an Nk-type transcription factor most homologous to vertebrate Nkx6.1 and Nkx6.2. The homeodomains and NK decapeptide domains of all three proteins are highly conserved. Nk6 is expressed in the embryonic brain, ventral nerve cord, hindgut, and internal head structures. Nerve cord expression is in midline precursors, several ventral and intermediate column neuroblasts, and later in neurons but not glia, similar to the known expression of Nkx6 genes in the neural tube. We show genetically that Nk6 is positively regulated, directly or indirectly, by vnd in brain precursors. In vnd mutants, head neuroectoderm Nk6 expression is abolished where it is normally co-expressed with vnd. Conversely, vnd-overexpression leads to ectopic Nk6 expression in the brain. These findings further highlight the importance of interactions between Nk(x)-type genes in regulating their expression." @default.
- W2000306719 created "2016-06-24" @default.
- W2000306719 creator A5021088512 @default.
- W2000306719 creator A5051796970 @default.
- W2000306719 creator A5068977419 @default.
- W2000306719 creator A5079253030 @default.
- W2000306719 creator A5088327236 @default.
- W2000306719 date "2002-08-01" @default.
- W2000306719 modified "2023-09-29" @default.
- W2000306719 title "Nk6, a novel Drosophila homeobox gene regulated by vnd" @default.
- W2000306719 cites W1482845445 @default.
- W2000306719 cites W1497961594 @default.
- W2000306719 cites W1515422163 @default.
- W2000306719 cites W1538129425 @default.
- W2000306719 cites W1585313030 @default.
- W2000306719 cites W1807161409 @default.
- W2000306719 cites W188998665 @default.
- W2000306719 cites W1892276981 @default.
- W2000306719 cites W1898282649 @default.
- W2000306719 cites W1971695061 @default.
- W2000306719 cites W1974215719 @default.
- W2000306719 cites W1991777044 @default.
- W2000306719 cites W1996775753 @default.
- W2000306719 cites W1997707404 @default.
- W2000306719 cites W2003092586 @default.
- W2000306719 cites W2005321694 @default.
- W2000306719 cites W2014479208 @default.
- W2000306719 cites W2014908429 @default.
- W2000306719 cites W2016748203 @default.
- W2000306719 cites W2018630778 @default.
- W2000306719 cites W2020160059 @default.
- W2000306719 cites W2041619316 @default.
- W2000306719 cites W2044344777 @default.
- W2000306719 cites W2053352747 @default.
- W2000306719 cites W2058039243 @default.
- W2000306719 cites W2059132747 @default.
- W2000306719 cites W2066729924 @default.
- W2000306719 cites W2072515549 @default.
- W2000306719 cites W2078694814 @default.
- W2000306719 cites W2082154860 @default.
- W2000306719 cites W2087530182 @default.
- W2000306719 cites W2088658701 @default.
- W2000306719 cites W2090693983 @default.
- W2000306719 cites W2094035169 @default.
- W2000306719 cites W2094330460 @default.
- W2000306719 cites W2097065859 @default.
- W2000306719 cites W2102960786 @default.
- W2000306719 cites W2109597876 @default.
- W2000306719 cites W2109899567 @default.
- W2000306719 cites W2110643873 @default.
- W2000306719 cites W2120191166 @default.
- W2000306719 cites W2123933036 @default.
- W2000306719 cites W2133488136 @default.
- W2000306719 cites W2133708115 @default.
- W2000306719 cites W2135456421 @default.
- W2000306719 cites W2141128578 @default.
- W2000306719 cites W2141267751 @default.
- W2000306719 cites W2141671204 @default.
- W2000306719 cites W2142228333 @default.
- W2000306719 cites W2143965788 @default.
- W2000306719 cites W2144274759 @default.
- W2000306719 cites W2149925209 @default.
- W2000306719 cites W2158714788 @default.
- W2000306719 cites W2159613449 @default.
- W2000306719 cites W2165349943 @default.
- W2000306719 cites W2167721895 @default.
- W2000306719 cites W2171019508 @default.
- W2000306719 cites W2177609029 @default.
- W2000306719 cites W2202555492 @default.
- W2000306719 cites W2223979714 @default.
- W2000306719 cites W2298995761 @default.
- W2000306719 cites W4063809 @default.
- W2000306719 cites W4248042899 @default.
- W2000306719 cites W4297692503 @default.
- W2000306719 doi "https://doi.org/10.1016/s0925-4773(02)00155-7" @default.
- W2000306719 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12128210" @default.
- W2000306719 hasPublicationYear "2002" @default.
- W2000306719 type Work @default.
- W2000306719 sameAs 2000306719 @default.
- W2000306719 citedByCount "23" @default.
- W2000306719 countsByYear W20003067192013 @default.
- W2000306719 crossrefType "journal-article" @default.
- W2000306719 hasAuthorship W2000306719A5021088512 @default.
- W2000306719 hasAuthorship W2000306719A5051796970 @default.
- W2000306719 hasAuthorship W2000306719A5068977419 @default.
- W2000306719 hasAuthorship W2000306719A5079253030 @default.
- W2000306719 hasAuthorship W2000306719A5088327236 @default.
- W2000306719 hasConcept C104317684 @default.
- W2000306719 hasConcept C121587040 @default.
- W2000306719 hasConcept C135073763 @default.
- W2000306719 hasConcept C143065580 @default.
- W2000306719 hasConcept C145103041 @default.
- W2000306719 hasConcept C158944026 @default.
- W2000306719 hasConcept C169760540 @default.
- W2000306719 hasConcept C196287685 @default.
- W2000306719 hasConcept C2780915607 @default.
- W2000306719 hasConcept C39961270 @default.
- W2000306719 hasConcept C4746552 @default.