Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000308003> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W2000308003 abstract "The purpose of this study was to investigate the interaction of heat and chemotherapy in experimental whole body hyperthermia (WBH). A vascular technique of extracorporeal perfusion was employed to rapidly elevate body temperature in rabbits carrying the transplantable VX-2 carcinoma. Hyperthermia (greater than 41 degrees C) was achieved in a mean time of 28 minutes. Tumor-bearing rabbits receiving WBH alone exhibited poor mean survival (14 days) relative to untreated tumor-bearing animals (32 days) and the group receiving IV Cis-platinum alone (50 days) (NS, p less than .05 respectively). WBH with Cis-platinum was intermediate in terms of mean survival (30 days, NS) between the WBH alone and Cis-platinum alone groups. In this experimental model we have determined WBH to be a detrimental form of cancer therapy. Its action appears to enhance tumor proliferation, resulting in rapid animal demise. In light of these findings a reevaluation of clinical WBH may be warranted." @default.
- W2000308003 created "2016-06-24" @default.
- W2000308003 creator A5038930255 @default.
- W2000308003 creator A5056446783 @default.
- W2000308003 creator A5085393263 @default.
- W2000308003 date "1983-10-01" @default.
- W2000308003 modified "2023-09-25" @default.
- W2000308003 title "Enhanced tumor growth in experimental whole body hyperthermia" @default.
- W2000308003 cites W1499520031 @default.
- W2000308003 cites W1507512036 @default.
- W2000308003 cites W1977689814 @default.
- W2000308003 cites W1984823936 @default.
- W2000308003 cites W1997131248 @default.
- W2000308003 cites W2023989387 @default.
- W2000308003 cites W2029910544 @default.
- W2000308003 cites W2040687622 @default.
- W2000308003 cites W2047987049 @default.
- W2000308003 cites W2057915940 @default.
- W2000308003 cites W2058522924 @default.
- W2000308003 cites W2071342171 @default.
- W2000308003 cites W2086345225 @default.
- W2000308003 cites W2089383415 @default.
- W2000308003 cites W2093558900 @default.
- W2000308003 cites W2109346835 @default.
- W2000308003 cites W2419298244 @default.
- W2000308003 cites W2616511690 @default.
- W2000308003 cites W4244326439 @default.
- W2000308003 doi "https://doi.org/10.1002/jso.2930240211" @default.
- W2000308003 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6685213" @default.
- W2000308003 hasPublicationYear "1983" @default.
- W2000308003 type Work @default.
- W2000308003 sameAs 2000308003 @default.
- W2000308003 citedByCount "2" @default.
- W2000308003 crossrefType "journal-article" @default.
- W2000308003 hasAuthorship W2000308003A5038930255 @default.
- W2000308003 hasAuthorship W2000308003A5056446783 @default.
- W2000308003 hasAuthorship W2000308003A5085393263 @default.
- W2000308003 hasConcept C126322002 @default.
- W2000308003 hasConcept C141071460 @default.
- W2000308003 hasConcept C146957229 @default.
- W2000308003 hasConcept C2776694085 @default.
- W2000308003 hasConcept C2779915274 @default.
- W2000308003 hasConcept C2779949491 @default.
- W2000308003 hasConcept C42219234 @default.
- W2000308003 hasConcept C71924100 @default.
- W2000308003 hasConceptScore W2000308003C126322002 @default.
- W2000308003 hasConceptScore W2000308003C141071460 @default.
- W2000308003 hasConceptScore W2000308003C146957229 @default.
- W2000308003 hasConceptScore W2000308003C2776694085 @default.
- W2000308003 hasConceptScore W2000308003C2779915274 @default.
- W2000308003 hasConceptScore W2000308003C2779949491 @default.
- W2000308003 hasConceptScore W2000308003C42219234 @default.
- W2000308003 hasConceptScore W2000308003C71924100 @default.
- W2000308003 hasLocation W20003080031 @default.
- W2000308003 hasLocation W20003080032 @default.
- W2000308003 hasOpenAccess W2000308003 @default.
- W2000308003 hasPrimaryLocation W20003080031 @default.
- W2000308003 hasRelatedWork W2130474357 @default.
- W2000308003 hasRelatedWork W2349484018 @default.
- W2000308003 hasRelatedWork W2376381626 @default.
- W2000308003 hasRelatedWork W2378831661 @default.
- W2000308003 hasRelatedWork W2386765994 @default.
- W2000308003 hasRelatedWork W2388140389 @default.
- W2000308003 hasRelatedWork W2394086538 @default.
- W2000308003 hasRelatedWork W2410278223 @default.
- W2000308003 hasRelatedWork W2605800150 @default.
- W2000308003 hasRelatedWork W3146341646 @default.
- W2000308003 isParatext "false" @default.
- W2000308003 isRetracted "false" @default.
- W2000308003 magId "2000308003" @default.
- W2000308003 workType "article" @default.