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- W2000308048 abstract "<i>Background:</i> To evaluate the effectof povidone-iodine liposome hydrogel on colonic anastomosis. <i>Methods:</i> 70 Wistar-Albino male rats were randomly divided into seven groups. The left colon was transected and end-to-end anastomosis was performed. PVP-I liposome hydrogel was applied around the anastomoses in groups 2 and 5. Colonic bursting pressures and tissue hydroxyproline contents were measured on postoperative days 3 and 7. <i>Results:</i> PVP-I application did not cause any difference in the bursting pressures on postoperative day 3, but anastomotic strength was significantly increased by the use of PVP-I on postoperative day 7. The use of PVP-I liposome hydrogel had no effect on the level of perianastomotic hydroxyproline on postoperative day 3 but had positive effects on postoperativeday 7. <i>Conclusions:</i> We concluded that the beneficial effects of PVP-I liposome hydrogel might be due to the combination of broad-spectrum antimicrobial activity of PVP-I with the drug delivery properties and moisturizing molecular film effects of the liposome hydrogel." @default.
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- W2000308048 date "2005-01-01" @default.
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- W2000308048 title "Effect of Povidone-Iodine Liposome Hydrogel on Colonic Anastomosis" @default.
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- W2000308048 doi "https://doi.org/10.1159/000087870" @default.
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