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- W2000309355 abstract "To investigate the effect of pulmonary alveolar hypoxia on the sunthesis and release of endothelin (ET)-1, ET-1-like immunoreactivity (-LI) levels of the lung and plasma were measured in conscious unrestrained rats under hypoxic conditions. Sixty-min exposure to alveolar hypoxia (10 % O2 or 5 % O2) increased the ET-1-LI level in the lung. The plasma ET-1-LI level in hypoxic rats also increased significantly. The increase of plasma and lung ET-1-LI levels were parallel to the severity of hypoxia. These results demonstrates that acute pulmonary alveolar hypoxia increases lung and plasma ET-1-LI levels in conscious unrestrained rats, suggesting a possible physiological or pathophysiological significance of ET in alveolar hypoxia." @default.
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- W2000309355 date "1991-01-01" @default.
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- W2000309355 title "Acute pulmonary alveolar hypoxia increases lung and plasma endothelin-1 levels in conscious rats" @default.
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- W2000309355 doi "https://doi.org/10.1016/0024-3205(91)90362-f" @default.
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