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- W2000309929 abstract "In renal transplantation, ischemia/reperfusion (I/R) injury is related to production of reactive oxygen species. In addition to its antihypertensive action due to nonselective beta-adrenergic blocking activity, carvedilol has potent antioxidant activity. This study was designed to investigate the effects of carvedilol on I/R injury in rats. On postoperative days 2 and 4, serum creatinine levels were higher among the control and the metoprolol treatment groups compared with the carvedilol treatment group (P < .005). However, there were no significant differences on postoperative day 7. In conclusion, increased antioxidant modulation by carvedilol attenuated renal I/R injury." @default.
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- W2000309929 date "2008-09-01" @default.
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- W2000309929 title "Efficacy of Carvedilol for Ischemia/Reperfusion-Induced Oxidative Renal Injury in Rats" @default.
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- W2000309929 doi "https://doi.org/10.1016/j.transproceed.2008.07.083" @default.
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