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- W2000312462 abstract "Capsule endoscopy (CE) allows simple non-invasive examination of the small intestine. This report examines diagnosis and outcome in a series of 26 patients with small bowel tumours detected by CE in three Australian Centres since its introduction. Twenty-seven tumours were identified in 26 patients from 416 CE studies (8F:18M). The mean age was 57 years (28–81). The mean duration of follow-up was 507 days (116-1044). Indications for CE were: obscure GI bleeding (21), suspected bowel tumour (3), abdominal pain (1) and diarrhoea (1). Most patients had no symptoms suggestive of small bowel obstruction and had undergone gastroscopy and colonoscopy prior to CE. Prior radiology, most of which was normal, had been performed in 23 of 26 patients (SB series 17, CT 16, both in 11) and enteroscopy in 7. Histology was available in 25 of the 26 patients. Tumours were resected in 23 patients (88%). One patient with presumed jejunal carcinoma declined surgery and is still undergoing regular transfusion. Eighteen tumours found at CE were malignant: 6 small bowel adenocarcinomas, 6 carcinoid tumours, (4 of these metastatic), 2 melanoma metastases, 2 GIST tumours, 1 colon carcinoma metastasis and 1 non-Hodgkin's lymphoma. Of the 5 patients with primary adenocarcinoma only one is disease free at follow-up. Three patients with carcinoid tumours have not had a recurrence, one of whom is now 34 months post resection. Both patients who had GIST tumours resected are disease free to date. The patients with melanoma have not had recurrent anaemia following resection. Other lesions included 4 hamartomas, 1 cystic lymphangioma, 1 primary amyloid and 1 small bowel lipoma. In 2 patients the tumours seen at capsule endoscopy were non-neoplastic: 1 heterotopic gastric mucosa and 1 inflammatory fibroid polyp. Resection was considered potentially curative in 9 of 23 patients (39%). Small bowel tumours are a significant finding at CE and are often unsuspected, not being found by other methods. In many patients detection of a tumour alters management and improves outcome. Even in malignant lesions, treatment is potentially curable in the absence of metastatic disease." @default.
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- W2000312462 date "2005-04-01" @default.
- W2000312462 modified "2023-09-27" @default.
- W2000312462 title "Diagnosis and Outcome of Small Bowel Tumours Found By Capsule Endoscopy: A Three Centre Australian Experience" @default.
- W2000312462 doi "https://doi.org/10.1016/s0016-5107(05)00887-4" @default.
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