Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000314084> ?p ?o ?g. }
- W2000314084 endingPage "43" @default.
- W2000314084 startingPage "34" @default.
- W2000314084 abstract "Hepatitis B virus (HBV) is a small, enveloped DNA virus which primarily infects liver cells and causes acute and persistent liver disease. Chronic HBV infection, frequently associated with cirrhosis and eventually hepatocellular carcinoma (HCC), represents a major health problem in the world. HBV is the prototype member of the hepadnavirus family, which includes several related mammalian viruses also implicated in liver carcinogenesis in the host. Although epidemiological evidence has clearly linked HBV infection with HCC development, the precise role of the virus and the molecular mechanisms of liver cell transformation remain elusive. Here we discuss potential oncogenic strategies of HBV, ranging from indirect mechanisms related to chronic necroinflammatory disease and to the effects of viral gene products on cell proliferation and apoptosis, to direct insertional activation of cellular (onco)genes. Presently, vaccination of high risk populations represents a major way to prevent the development of HBV-related liver cancer." @default.
- W2000314084 created "2016-06-24" @default.
- W2000314084 creator A5052907238 @default.
- W2000314084 date "1998-01-01" @default.
- W2000314084 modified "2023-10-04" @default.
- W2000314084 title "Hepatitis B viruses and cancerogenesis" @default.
- W2000314084 cites W1480852720 @default.
- W2000314084 cites W1505468269 @default.
- W2000314084 cites W1508483754 @default.
- W2000314084 cites W1525178335 @default.
- W2000314084 cites W158638529 @default.
- W2000314084 cites W1623494770 @default.
- W2000314084 cites W1651425720 @default.
- W2000314084 cites W1796170190 @default.
- W2000314084 cites W1939804351 @default.
- W2000314084 cites W1951553828 @default.
- W2000314084 cites W1974624271 @default.
- W2000314084 cites W1978922109 @default.
- W2000314084 cites W1986150533 @default.
- W2000314084 cites W2024668373 @default.
- W2000314084 cites W2030642077 @default.
- W2000314084 cites W2035794058 @default.
- W2000314084 cites W2037903080 @default.
- W2000314084 cites W2040358727 @default.
- W2000314084 cites W2047269669 @default.
- W2000314084 cites W2051087197 @default.
- W2000314084 cites W2052169714 @default.
- W2000314084 cites W2058349670 @default.
- W2000314084 cites W2064744782 @default.
- W2000314084 cites W2069781517 @default.
- W2000314084 cites W2075793367 @default.
- W2000314084 cites W2076684492 @default.
- W2000314084 cites W2081472291 @default.
- W2000314084 cites W2093019351 @default.
- W2000314084 cites W2096808350 @default.
- W2000314084 cites W2097587406 @default.
- W2000314084 cites W2113180849 @default.
- W2000314084 cites W2116298148 @default.
- W2000314084 cites W2122305232 @default.
- W2000314084 cites W2129923672 @default.
- W2000314084 cites W2140576094 @default.
- W2000314084 cites W2142466677 @default.
- W2000314084 cites W2144779965 @default.
- W2000314084 cites W2149175860 @default.
- W2000314084 cites W2151530333 @default.
- W2000314084 cites W2153556759 @default.
- W2000314084 cites W2166993990 @default.
- W2000314084 cites W2167063127 @default.
- W2000314084 cites W2167983057 @default.
- W2000314084 cites W2313449389 @default.
- W2000314084 cites W2322310797 @default.
- W2000314084 cites W2405173083 @default.
- W2000314084 cites W263045772 @default.
- W2000314084 cites W323412875 @default.
- W2000314084 cites W38016356 @default.
- W2000314084 cites W4246892132 @default.
- W2000314084 cites W61009196 @default.
- W2000314084 doi "https://doi.org/10.1016/s0753-3322(97)86239-7" @default.
- W2000314084 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9755793" @default.
- W2000314084 hasPublicationYear "1998" @default.
- W2000314084 type Work @default.
- W2000314084 sameAs 2000314084 @default.
- W2000314084 citedByCount "49" @default.
- W2000314084 countsByYear W20003140842012 @default.
- W2000314084 countsByYear W20003140842013 @default.
- W2000314084 countsByYear W20003140842015 @default.
- W2000314084 countsByYear W20003140842018 @default.
- W2000314084 countsByYear W20003140842019 @default.
- W2000314084 crossrefType "journal-article" @default.
- W2000314084 hasAuthorship W2000314084A5052907238 @default.
- W2000314084 hasConcept C104317684 @default.
- W2000314084 hasConcept C121608353 @default.
- W2000314084 hasConcept C141231307 @default.
- W2000314084 hasConcept C159047783 @default.
- W2000314084 hasConcept C203014093 @default.
- W2000314084 hasConcept C2522874641 @default.
- W2000314084 hasConcept C2776231280 @default.
- W2000314084 hasConcept C2777075537 @default.
- W2000314084 hasConcept C2777214474 @default.
- W2000314084 hasConcept C2777382497 @default.
- W2000314084 hasConcept C2778019345 @default.
- W2000314084 hasConcept C2779758228 @default.
- W2000314084 hasConcept C2780593183 @default.
- W2000314084 hasConcept C2780617729 @default.
- W2000314084 hasConcept C502942594 @default.
- W2000314084 hasConcept C54355233 @default.
- W2000314084 hasConcept C55493867 @default.
- W2000314084 hasConcept C555283112 @default.
- W2000314084 hasConcept C71924100 @default.
- W2000314084 hasConcept C86803240 @default.
- W2000314084 hasConcept C90924648 @default.
- W2000314084 hasConceptScore W2000314084C104317684 @default.
- W2000314084 hasConceptScore W2000314084C121608353 @default.
- W2000314084 hasConceptScore W2000314084C141231307 @default.
- W2000314084 hasConceptScore W2000314084C159047783 @default.
- W2000314084 hasConceptScore W2000314084C203014093 @default.
- W2000314084 hasConceptScore W2000314084C2522874641 @default.
- W2000314084 hasConceptScore W2000314084C2776231280 @default.