FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000314100> ?p ?o ?g. }

• W2000314100 endingPage "38" @default.
• W2000314100 startingPage "32" @default.
• W2000314100 abstract "The present study determined the Ca(2+)-dependence of the release of adenosine 5'-triphosphate (ATP) from dorsal spinal cord synaptosomes evoked by depolarization with K+ and capsaicin, and the effect of intrathecal capsaicin pretreatment, dorsal rhizotomy and intrathecal pretreatment with 6-hydroxydopamine on such release. Release of ATP evoked by K+ was Ca(2+)-dependent, while that evoked by capsaicin was Ca(2+)-independent. Capsaicin pretreatment (60 micrograms, 7 days), which lesions small diameter afferents, did not alter release of ATP evoked by either K+ or capsaicin. Dorsal rhizotomy, which lesions all afferents, produced a significant reduction in the amount of ATP released from the rhizotomized side compared to the intact side. Pretreatment with 6-hydroxydopamine (100 micrograms, 7 days) to destroy adrenergic nerve terminals, markedly reduced spinal cord noradrenaline levels, but did not alter the K(+)-evoked release of ATP. These results suggest that some K(+)-evoked release of ATP could originate from large but not small diameter afferent nerve terminals in the spinal cord. ATP does not appear to originate from small diameter afferents as, although ATP is released by in vitro exposure to capsaicin, such release occurs only at high concentrations, release is Ca(2+)-independent and it is unaltered by pretreatment with capsaicin. The bulk of the ATP released from the spinal cord does not originate from descending noradrenergic nerve terminals." @default.
• W2000314100 created "2016-06-24" @default.
• W2000314100 creator A5012815771 @default.
• W2000314100 creator A5014181246 @default.
• W2000314100 creator A5029413013 @default.
• W2000314100 creator A5052221889 @default.
• W2000314100 creator A5081454540 @default.
• W2000314100 date "1993-04-01" @default.
• W2000314100 modified "2023-10-16" @default.
• W2000314100 title "ATP release from dorsal spinal cord synaptosomes: characterization and neuronal origin" @default.
• W2000314100 cites W1965113135 @default.
• W2000314100 cites W1974705948 @default.
• W2000314100 cites W1976374962 @default.
• W2000314100 cites W1983014933 @default.
• W2000314100 cites W1983799169 @default.
• W2000314100 cites W1983929207 @default.
• W2000314100 cites W1993198667 @default.
• W2000314100 cites W1995833241 @default.
• W2000314100 cites W1996421895 @default.
• W2000314100 cites W2004624137 @default.
• W2000314100 cites W2007557024 @default.
• W2000314100 cites W2009994470 @default.
• W2000314100 cites W2011662666 @default.
• W2000314100 cites W2013231645 @default.
• W2000314100 cites W2034897107 @default.
• W2000314100 cites W2037364614 @default.
• W2000314100 cites W2038193150 @default.
• W2000314100 cites W2047374412 @default.
• W2000314100 cites W2049261807 @default.
• W2000314100 cites W2050241317 @default.
• W2000314100 cites W2052854972 @default.
• W2000314100 cites W2057615421 @default.
• W2000314100 cites W2066551451 @default.
• W2000314100 cites W2071489012 @default.
• W2000314100 cites W2073073327 @default.
• W2000314100 cites W2074054214 @default.
• W2000314100 cites W2075056521 @default.
• W2000314100 cites W2077018229 @default.
• W2000314100 cites W2130477360 @default.
• W2000314100 cites W2145379951 @default.
• W2000314100 cites W2151581816 @default.
• W2000314100 cites W2153936909 @default.
• W2000314100 cites W29616690 @default.
• W2000314100 doi "https://doi.org/10.1016/0006-8993(93)91213-c" @default.
• W2000314100 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8518929" @default.
• W2000314100 hasPublicationYear "1993" @default.
• W2000314100 type Work @default.
• W2000314100 sameAs 2000314100 @default.
• W2000314100 citedByCount "74" @default.
• W2000314100 countsByYear W20003141002012 @default.
• W2000314100 countsByYear W20003141002013 @default.
• W2000314100 countsByYear W20003141002014 @default.
• W2000314100 countsByYear W20003141002016 @default.
• W2000314100 countsByYear W20003141002017 @default.
• W2000314100 countsByYear W20003141002019 @default.
• W2000314100 countsByYear W20003141002020 @default.
• W2000314100 countsByYear W20003141002023 @default.
• W2000314100 crossrefType "journal-article" @default.
• W2000314100 hasAuthorship W2000314100A5012815771 @default.
• W2000314100 hasAuthorship W2000314100A5014181246 @default.
• W2000314100 hasAuthorship W2000314100A5029413013 @default.
• W2000314100 hasAuthorship W2000314100A5052221889 @default.
• W2000314100 hasAuthorship W2000314100A5081454540 @default.
• W2000314100 hasBestOaLocation W20003141002 @default.
• W2000314100 hasConcept C169760540 @default.
• W2000314100 hasConcept C170493617 @default.
• W2000314100 hasConcept C185592680 @default.
• W2000314100 hasConcept C2779846724 @default.
• W2000314100 hasConcept C2780051329 @default.
• W2000314100 hasConcept C2780775167 @default.
• W2000314100 hasConcept C42219234 @default.
• W2000314100 hasConcept C55493867 @default.
• W2000314100 hasConcept C71924100 @default.
• W2000314100 hasConcept C86803240 @default.
• W2000314100 hasConceptScore W2000314100C169760540 @default.
• W2000314100 hasConceptScore W2000314100C170493617 @default.
• W2000314100 hasConceptScore W2000314100C185592680 @default.
• W2000314100 hasConceptScore W2000314100C2779846724 @default.
• W2000314100 hasConceptScore W2000314100C2780051329 @default.
• W2000314100 hasConceptScore W2000314100C2780775167 @default.
• W2000314100 hasConceptScore W2000314100C42219234 @default.
• W2000314100 hasConceptScore W2000314100C55493867 @default.
• W2000314100 hasConceptScore W2000314100C71924100 @default.
• W2000314100 hasConceptScore W2000314100C86803240 @default.
• W2000314100 hasIssue "1" @default.
• W2000314100 hasLocation W20003141001 @default.
• W2000314100 hasLocation W20003141002 @default.
• W2000314100 hasLocation W20003141003 @default.
• W2000314100 hasOpenAccess W2000314100 @default.
• W2000314100 hasPrimaryLocation W20003141001 @default.
• W2000314100 hasRelatedWork W1813296873 @default.
• W2000314100 hasRelatedWork W1979316334 @default.
• W2000314100 hasRelatedWork W2017823590 @default.
• W2000314100 hasRelatedWork W2037590378 @default.
• W2000314100 hasRelatedWork W2071666492 @default.
• W2000314100 hasRelatedWork W2153054222 @default.
• W2000314100 hasRelatedWork W2159248936 @default.
• W2000314100 hasRelatedWork W2167243738 @default.

• next