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- W2000316172 abstract "Three 14C-labeled steroids (17-hydroxyprogesterone, deoxycorticosterone, and cortisol) were placed in nmol amounts into intestinal loops of male dogs. The effluent portal blood, intestinal tissue and intestinal contents were analyzed for metabolites. The metabolites were purified and partially separated on Florisil columns and by t.l.c., and quantitated with liquid scintillation counting. In all experiments there was rapid and extensive conversion of the substrate to unconjugated metabolites. With one exception, C-4 double bond reduction yielded steroids with the 5α-conformation. 17-Hydroxyprogesterone yielded the largest and cortisol the smallest number of metabolites." @default.
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- W2000316172 date "1979-09-01" @default.
- W2000316172 modified "2023-09-25" @default.
- W2000316172 title "Intestinal absorption and metabolism of 17-hydroxyprogesterone, deoxycorticosterone and cortisol in the dog" @default.
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- W2000316172 doi "https://doi.org/10.1016/0022-4731(79)90186-9" @default.
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