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- W2000318788 abstract "The size of the receptive field of retinal horizontal cells changes with the state of dark/light adaptation. We have used a mathematical model to determine how changes in the membrane conductance affect the receptive-field properties of horizontal cells. We first modeled the nonlinear membrane properties of horizontal cells based on ionic current mechanisms. The dissociated horizontal cell model reproduced the voltage-current (V-I) relationships for various extracellular glutamate concentrations measured in electrophysiological studies. Second, a network horizontal cell model was also described, and it reproduced the V-I relationship observed in vivo. The network model showed a bell-shaped relationship between the receptive-field size and constant glutamate concentration. The simulated results suggest that the calcium current is a candidate for the bell-shaped length constant relationship." @default.
- W2000318788 created "2016-06-24" @default.
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- W2000318788 date "2005-01-01" @default.
- W2000318788 modified "2023-09-26" @default.
- W2000318788 title "Simulation analysis of receptive-field size of retinal horizontal cells by ionic current model" @default.
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- W2000318788 doi "https://doi.org/10.1017/s0952523805221107" @default.
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