Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000322407> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W2000322407 endingPage "5679" @default.
- W2000322407 startingPage "5678" @default.
- W2000322407 abstract "Arabidopsis thaliana is a well-established model organism for plant genetics, and its recently sequenced genome reveals a wealth of enzymes similar to known examples that biosynthesize secondary metabolites. We describe experiments that exploit this genomic information to identify novel terpenoids. A predicted open reading frame with high similarity to known oxidosqualene cyclases was shown to convert 3(S)-oxidosqualene to the previously unknown triterpene alcohol (3S,13S,14R)-malabarica-8,17,21-trien-3-ol, which we named thalianol. Genome mining offers a systematic approach to exhaustively characterize the biosynthetic potential of an organism, and is considerably more sensitive than classical approaches. Because even rare transcripts can be heterologously expressed at high levels, genome mining coupled to heterologous expression may be more sensitive than classical extraction approaches for isolating and characterizing trace metabolites." @default.
- W2000322407 created "2016-06-24" @default.
- W2000322407 creator A5011050541 @default.
- W2000322407 creator A5038086364 @default.
- W2000322407 creator A5060246541 @default.
- W2000322407 date "2004-04-17" @default.
- W2000322407 modified "2023-10-16" @default.
- W2000322407 title "Genome Mining To Identify New Plant Triterpenoids" @default.
- W2000322407 cites W1567072612 @default.
- W2000322407 cites W1988169038 @default.
- W2000322407 cites W2022897435 @default.
- W2000322407 cites W2030319521 @default.
- W2000322407 cites W2034857002 @default.
- W2000322407 cites W2036987057 @default.
- W2000322407 cites W2038472202 @default.
- W2000322407 cites W2042001074 @default.
- W2000322407 cites W2044717234 @default.
- W2000322407 cites W2045393309 @default.
- W2000322407 cites W2047450113 @default.
- W2000322407 cites W2057462478 @default.
- W2000322407 cites W2088417665 @default.
- W2000322407 cites W2318955028 @default.
- W2000322407 doi "https://doi.org/10.1021/ja0318784" @default.
- W2000322407 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15125655" @default.
- W2000322407 hasPublicationYear "2004" @default.
- W2000322407 type Work @default.
- W2000322407 sameAs 2000322407 @default.
- W2000322407 citedByCount "79" @default.
- W2000322407 countsByYear W20003224072012 @default.
- W2000322407 countsByYear W20003224072013 @default.
- W2000322407 countsByYear W20003224072014 @default.
- W2000322407 countsByYear W20003224072016 @default.
- W2000322407 countsByYear W20003224072017 @default.
- W2000322407 countsByYear W20003224072018 @default.
- W2000322407 countsByYear W20003224072019 @default.
- W2000322407 countsByYear W20003224072020 @default.
- W2000322407 countsByYear W20003224072021 @default.
- W2000322407 countsByYear W20003224072022 @default.
- W2000322407 countsByYear W20003224072023 @default.
- W2000322407 crossrefType "journal-article" @default.
- W2000322407 hasAuthorship W2000322407A5011050541 @default.
- W2000322407 hasAuthorship W2000322407A5038086364 @default.
- W2000322407 hasAuthorship W2000322407A5060246541 @default.
- W2000322407 hasConcept C104317684 @default.
- W2000322407 hasConcept C137858568 @default.
- W2000322407 hasConcept C141231307 @default.
- W2000322407 hasConcept C142724271 @default.
- W2000322407 hasConcept C143065580 @default.
- W2000322407 hasConcept C185592680 @default.
- W2000322407 hasConcept C204787440 @default.
- W2000322407 hasConcept C2775988993 @default.
- W2000322407 hasConcept C2780527577 @default.
- W2000322407 hasConcept C54355233 @default.
- W2000322407 hasConcept C70721500 @default.
- W2000322407 hasConcept C71924100 @default.
- W2000322407 hasConcept C86803240 @default.
- W2000322407 hasConceptScore W2000322407C104317684 @default.
- W2000322407 hasConceptScore W2000322407C137858568 @default.
- W2000322407 hasConceptScore W2000322407C141231307 @default.
- W2000322407 hasConceptScore W2000322407C142724271 @default.
- W2000322407 hasConceptScore W2000322407C143065580 @default.
- W2000322407 hasConceptScore W2000322407C185592680 @default.
- W2000322407 hasConceptScore W2000322407C204787440 @default.
- W2000322407 hasConceptScore W2000322407C2775988993 @default.
- W2000322407 hasConceptScore W2000322407C2780527577 @default.
- W2000322407 hasConceptScore W2000322407C54355233 @default.
- W2000322407 hasConceptScore W2000322407C70721500 @default.
- W2000322407 hasConceptScore W2000322407C71924100 @default.
- W2000322407 hasConceptScore W2000322407C86803240 @default.
- W2000322407 hasIssue "18" @default.
- W2000322407 hasLocation W20003224071 @default.
- W2000322407 hasLocation W20003224072 @default.
- W2000322407 hasOpenAccess W2000322407 @default.
- W2000322407 hasPrimaryLocation W20003224071 @default.
- W2000322407 hasRelatedWork W1991523530 @default.
- W2000322407 hasRelatedWork W2000322407 @default.
- W2000322407 hasRelatedWork W2002128513 @default.
- W2000322407 hasRelatedWork W2020824267 @default.
- W2000322407 hasRelatedWork W2030640333 @default.
- W2000322407 hasRelatedWork W2051673493 @default.
- W2000322407 hasRelatedWork W2346836489 @default.
- W2000322407 hasRelatedWork W2398694905 @default.
- W2000322407 hasRelatedWork W4256460412 @default.
- W2000322407 hasRelatedWork W2092874662 @default.
- W2000322407 hasVolume "126" @default.
- W2000322407 isParatext "false" @default.
- W2000322407 isRetracted "false" @default.
- W2000322407 magId "2000322407" @default.
- W2000322407 workType "article" @default.