FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000329517> ?p ?o ?g. }

• W2000329517 endingPage "1025" @default.
• W2000329517 startingPage "1020" @default.
• W2000329517 abstract "Cell culture and biochemical procedures were used to identify and study the possible mechanisms regulating the secretion of GnRH-like immunoreactivity (GnRH-LI) from human placenta. Monolayer primary cultures of trophoblasts were established after mechanical and enzymatic dispersion of normal human term placenta. The cultured cells stained immunocytochemically positive with anti-GnRH serum, and GnRH-LI extracted from the cells eluted from high performance liquid chromatography with the same retention time as authentic GnRH. One week after plating, exposure to high concentrations of K+ or to various doses of veratridine, a Na+ ionophore, increased GnRH-LI release into the culture medium. This effect was reversed by Ca2+ antagonists (cobalt, EGTA, and verapamil). Dibutyrylcyclic AMP, forskolin, theophylline, and theobromine also increased GnRH-LI concentrations in the medium of cultured placental cells in a dose-related manner, as did prostaglandins E2 and F2 alpha and epinephrine. The effect of epinephrine on GnRH-LI concentrations was mimicked by isoproterenol and reversed by propranolol, suggesting an effect mediated by beta-adrenergic receptors. These results indicate that GnRH-LI release from cultured human placental cells is stimulated by the opening of ionic channels and activation of the adenylate cyclase/cAMP system, and that prostaglandins and epinephrine may be involved in the regulation of GnRH-LI release from human placenta." @default.
• W2000329517 created "2016-06-24" @default.
• W2000329517 creator A5028504214 @default.
• W2000329517 creator A5033348306 @default.
• W2000329517 creator A5049594185 @default.
• W2000329517 date "1987-11-01" @default.
• W2000329517 modified "2023-10-16" @default.
• W2000329517 title "Adenosine 3′,5′-Monophosphate, Prostaglandins, and Epinephrine Stimulate the Secretion of Immunoreactive Gonadotropin-Releasing Hormone from Cultured Human Placental Cells*" @default.
• W2000329517 cites W1472451706 @default.
• W2000329517 cites W1547962593 @default.
• W2000329517 cites W1555060635 @default.
• W2000329517 cites W1610873903 @default.
• W2000329517 cites W1787654591 @default.
• W2000329517 cites W1983956535 @default.
• W2000329517 cites W1984891135 @default.
• W2000329517 cites W1998605006 @default.
• W2000329517 cites W2002498542 @default.
• W2000329517 cites W2005066622 @default.
• W2000329517 cites W2010587851 @default.
• W2000329517 cites W2020946333 @default.
• W2000329517 cites W2025881104 @default.
• W2000329517 cites W2039297050 @default.
• W2000329517 cites W2058891878 @default.
• W2000329517 cites W2061563232 @default.
• W2000329517 cites W2067099396 @default.
• W2000329517 cites W2080065770 @default.
• W2000329517 cites W2080829357 @default.
• W2000329517 cites W2093462976 @default.
• W2000329517 cites W2123209211 @default.
• W2000329517 cites W2142814029 @default.
• W2000329517 cites W2155490454 @default.
• W2000329517 cites W2158034048 @default.
• W2000329517 cites W2167503858 @default.
• W2000329517 cites W2270417141 @default.
• W2000329517 cites W2412345898 @default.
• W2000329517 cites W2412965617 @default.
• W2000329517 doi "https://doi.org/10.1210/jcem-65-5-1020" @default.
• W2000329517 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3312277" @default.
• W2000329517 hasPublicationYear "1987" @default.
• W2000329517 type Work @default.
• W2000329517 sameAs 2000329517 @default.
• W2000329517 citedByCount "65" @default.
• W2000329517 countsByYear W20003295172012 @default.
• W2000329517 countsByYear W20003295172015 @default.
• W2000329517 countsByYear W20003295172016 @default.
• W2000329517 countsByYear W20003295172017 @default.
• W2000329517 countsByYear W20003295172018 @default.
• W2000329517 crossrefType "journal-article" @default.
• W2000329517 hasAuthorship W2000329517A5028504214 @default.
• W2000329517 hasAuthorship W2000329517A5033348306 @default.
• W2000329517 hasAuthorship W2000329517A5049594185 @default.
• W2000329517 hasConcept C126322002 @default.
• W2000329517 hasConcept C134018914 @default.
• W2000329517 hasConcept C178790620 @default.
• W2000329517 hasConcept C185592680 @default.
• W2000329517 hasConcept C24998067 @default.
• W2000329517 hasConcept C2775859304 @default.
• W2000329517 hasConcept C2776986425 @default.
• W2000329517 hasConcept C2776991684 @default.
• W2000329517 hasConcept C2778575703 @default.
• W2000329517 hasConcept C2778894405 @default.
• W2000329517 hasConcept C2779276759 @default.
• W2000329517 hasConcept C50952357 @default.
• W2000329517 hasConcept C537181965 @default.
• W2000329517 hasConcept C71315377 @default.
• W2000329517 hasConcept C71924100 @default.
• W2000329517 hasConcept C86803240 @default.
• W2000329517 hasConceptScore W2000329517C126322002 @default.
• W2000329517 hasConceptScore W2000329517C134018914 @default.
• W2000329517 hasConceptScore W2000329517C178790620 @default.
• W2000329517 hasConceptScore W2000329517C185592680 @default.
• W2000329517 hasConceptScore W2000329517C24998067 @default.
• W2000329517 hasConceptScore W2000329517C2775859304 @default.
• W2000329517 hasConceptScore W2000329517C2776986425 @default.
• W2000329517 hasConceptScore W2000329517C2776991684 @default.
• W2000329517 hasConceptScore W2000329517C2778575703 @default.
• W2000329517 hasConceptScore W2000329517C2778894405 @default.
• W2000329517 hasConceptScore W2000329517C2779276759 @default.
• W2000329517 hasConceptScore W2000329517C50952357 @default.
• W2000329517 hasConceptScore W2000329517C537181965 @default.
• W2000329517 hasConceptScore W2000329517C71315377 @default.
• W2000329517 hasConceptScore W2000329517C71924100 @default.
• W2000329517 hasConceptScore W2000329517C86803240 @default.
• W2000329517 hasIssue "5" @default.
• W2000329517 hasLocation W20003295171 @default.
• W2000329517 hasLocation W20003295172 @default.
• W2000329517 hasOpenAccess W2000329517 @default.
• W2000329517 hasPrimaryLocation W20003295171 @default.
• W2000329517 hasRelatedWork W1586976590 @default.
• W2000329517 hasRelatedWork W1965566289 @default.
• W2000329517 hasRelatedWork W2007885146 @default.
• W2000329517 hasRelatedWork W2058991568 @default.
• W2000329517 hasRelatedWork W2086098588 @default.
• W2000329517 hasRelatedWork W2089092795 @default.
• W2000329517 hasRelatedWork W2141504910 @default.
• W2000329517 hasRelatedWork W2170466589 @default.
• W2000329517 hasRelatedWork W2171532347 @default.
• W2000329517 hasRelatedWork W2398262967 @default.

• next