Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000329992> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W2000329992 endingPage "62" @default.
- W2000329992 startingPage "53" @default.
- W2000329992 abstract "We examined the cell cycle distribution and subset marker characteristics of mucosal-associated supramammary lymph node (MALN) T cell subpopulations at sites proximal and distal to the mammary region of animals repeatedly injected with Staphylococcus aureus antigen. Multiparameter flow cytometric analysis of draining MALNs showed that CD4+ T cells expressed significantly greater amounts of CD4 surface antigen than corresponding cell populations in non-draining MALNs. In contrast, the intensity of CD8 surface antigen expression among draining MALN CD8+ cells remained unchanged. Draining and non-draining MALNs contained nearly equal proportions of large CD4+ T cell subpopulations (CD4/CD8 ratio) with the former having greater cell numbers undergoing active DNA synthesis (S + G2M phase) in vivo. Similarly, draining MALNs had greater cell numbers of small CD4+ lymphocytes in the S + G2M phase, although with lower CD4/CD8 ratios of corresponding cell populations in non-draining MALNs. This study demonstrates that prolonged exposure with Staph aureus antigen enhances the cell number and expression of CD4 surface antigen among T lymphocyte subpopulations actively synthesizing DNA in draining MALNs. The role of the CD4 antigen in inflammatory responses at sites proximal (draining) and distal (non draining) to chronic infection within the mammary/mucosal immune network is discussed." @default.
- W2000329992 created "2016-06-24" @default.
- W2000329992 creator A5024693990 @default.
- W2000329992 creator A5054601838 @default.
- W2000329992 date "1992-06-01" @default.
- W2000329992 modified "2023-10-16" @default.
- W2000329992 title "Elevated CD4 Antigen Expression Among Activated T Cells in Lymph Nodes Draining Mammary Regions Chronically Exposed to Staphylococcus aureus Antigen" @default.
- W2000329992 cites W1965546222 @default.
- W2000329992 cites W1966286149 @default.
- W2000329992 cites W1972240086 @default.
- W2000329992 cites W1986417404 @default.
- W2000329992 cites W1995138988 @default.
- W2000329992 cites W2025701387 @default.
- W2000329992 cites W2031399992 @default.
- W2000329992 cites W2073151324 @default.
- W2000329992 cites W2080627154 @default.
- W2000329992 cites W2085447366 @default.
- W2000329992 cites W2125650988 @default.
- W2000329992 cites W2169790726 @default.
- W2000329992 cites W4211067088 @default.
- W2000329992 doi "https://doi.org/10.1016/s0171-2985(11)80317-7" @default.
- W2000329992 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1356910" @default.
- W2000329992 hasPublicationYear "1992" @default.
- W2000329992 type Work @default.
- W2000329992 sameAs 2000329992 @default.
- W2000329992 citedByCount "2" @default.
- W2000329992 countsByYear W20003299922017 @default.
- W2000329992 crossrefType "journal-article" @default.
- W2000329992 hasAuthorship W2000329992A5024693990 @default.
- W2000329992 hasAuthorship W2000329992A5054601838 @default.
- W2000329992 hasConcept C142724271 @default.
- W2000329992 hasConcept C147483822 @default.
- W2000329992 hasConcept C153911025 @default.
- W2000329992 hasConcept C154317977 @default.
- W2000329992 hasConcept C167672396 @default.
- W2000329992 hasConcept C202751555 @default.
- W2000329992 hasConcept C203014093 @default.
- W2000329992 hasConcept C2776090121 @default.
- W2000329992 hasConcept C2779489039 @default.
- W2000329992 hasConcept C2779720271 @default.
- W2000329992 hasConcept C2780849966 @default.
- W2000329992 hasConcept C2992881475 @default.
- W2000329992 hasConcept C523546767 @default.
- W2000329992 hasConcept C54355233 @default.
- W2000329992 hasConcept C55493867 @default.
- W2000329992 hasConcept C71924100 @default.
- W2000329992 hasConcept C86803240 @default.
- W2000329992 hasConcept C8891405 @default.
- W2000329992 hasConceptScore W2000329992C142724271 @default.
- W2000329992 hasConceptScore W2000329992C147483822 @default.
- W2000329992 hasConceptScore W2000329992C153911025 @default.
- W2000329992 hasConceptScore W2000329992C154317977 @default.
- W2000329992 hasConceptScore W2000329992C167672396 @default.
- W2000329992 hasConceptScore W2000329992C202751555 @default.
- W2000329992 hasConceptScore W2000329992C203014093 @default.
- W2000329992 hasConceptScore W2000329992C2776090121 @default.
- W2000329992 hasConceptScore W2000329992C2779489039 @default.
- W2000329992 hasConceptScore W2000329992C2779720271 @default.
- W2000329992 hasConceptScore W2000329992C2780849966 @default.
- W2000329992 hasConceptScore W2000329992C2992881475 @default.
- W2000329992 hasConceptScore W2000329992C523546767 @default.
- W2000329992 hasConceptScore W2000329992C54355233 @default.
- W2000329992 hasConceptScore W2000329992C55493867 @default.
- W2000329992 hasConceptScore W2000329992C71924100 @default.
- W2000329992 hasConceptScore W2000329992C86803240 @default.
- W2000329992 hasConceptScore W2000329992C8891405 @default.
- W2000329992 hasIssue "1" @default.
- W2000329992 hasLocation W20003299921 @default.
- W2000329992 hasLocation W20003299922 @default.
- W2000329992 hasOpenAccess W2000329992 @default.
- W2000329992 hasPrimaryLocation W20003299921 @default.
- W2000329992 hasRelatedWork W1505145311 @default.
- W2000329992 hasRelatedWork W1513178816 @default.
- W2000329992 hasRelatedWork W1967253370 @default.
- W2000329992 hasRelatedWork W2009142726 @default.
- W2000329992 hasRelatedWork W2018916009 @default.
- W2000329992 hasRelatedWork W2220102944 @default.
- W2000329992 hasRelatedWork W2415525140 @default.
- W2000329992 hasRelatedWork W2473523216 @default.
- W2000329992 hasRelatedWork W2793511401 @default.
- W2000329992 hasRelatedWork W4236372834 @default.
- W2000329992 hasVolume "185" @default.
- W2000329992 isParatext "false" @default.
- W2000329992 isRetracted "false" @default.
- W2000329992 magId "2000329992" @default.
- W2000329992 workType "article" @default.