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• W2000331194 abstract "To develop a model to predict the probability of endoscopic third ventriculostomy (ETV) success in the treatment for hydrocephalus on the basis of a child's individual characteristics.We analyzed 618 ETVs performed consecutively on children at 12 international institutions to identify predictors of ETV success at 6 months. A multivariable logistic regression model was developed on 70% of the dataset (training set) and validated on 30% of the dataset (validation set).In the training set, 305/455 ETVs (67.0%) were successful. The regression model (containing patient age, cause of hydrocephalus, and previous cerebrospinal fluid shunt) demonstrated good fit (Hosmer-Lemeshow, P = .78) and discrimination (C statistic = 0.70). In the validation set, 105/163 ETVs (64.4%) were successful and the model maintained good fit (Hosmer-Lemeshow, P = .45), discrimination (C statistic = 0.68), and calibration (calibration slope = 0.88). A simplified ETV Success Score was devised that closely approximates the predicted probability of ETV success.Children most likely to succeed with ETV can now be accurately identified and spared the long-term complications of CSF shunting." @default.
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• W2000331194 date "2009-08-01" @default.
• W2000331194 modified "2023-10-13" @default.
• W2000331194 title "Endoscopic Third Ventriculostomy in the Treatment of Childhood Hydrocephalus" @default.
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• W2000331194 doi "https://doi.org/10.1016/j.jpeds.2009.02.048" @default.
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