Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000331857> ?p ?o ?g. }
- W2000331857 endingPage "311" @default.
- W2000331857 startingPage "303" @default.
- W2000331857 abstract "The RASSF (Ras-association domain family) has recently gained several new members and now contains ten proteins (RASSF1-10), several of which are potential tumour suppressors. The family can be split into two groups, the classical RASSF proteins (RASSF1-6) and the four recently added N-terminal RASSF proteins (RASSF7-10). The N-terminal RASSF proteins have a number of differences from the classical RASSF members and represent a newly defined set of potential Ras effectors. They have been linked to key biological processes, including cell death, proliferation, microtubule stability, promoter methylation, vesicle trafficking and response to hypoxia. Two members of the N-terminal RASSF family have also been highlighted as potential tumour suppressors. The present review will summarize what is known about the N-terminal RASSF proteins, addressing their function and possible links to cancer formation. It will also compare the N-terminal RASSF proteins with the classical RASSF proteins and ask whether the N-terminal RASSF proteins should be considered as genuine members or imposters in the RASSF family." @default.
- W2000331857 created "2016-06-24" @default.
- W2000331857 creator A5053255525 @default.
- W2000331857 creator A5056133155 @default.
- W2000331857 creator A5058111655 @default.
- W2000331857 creator A5059695474 @default.
- W2000331857 creator A5082083017 @default.
- W2000331857 date "2009-12-23" @default.
- W2000331857 modified "2023-09-26" @default.
- W2000331857 title "The N-terminal RASSF family: a new group of Ras-association-domaincontaining proteins, with emerging links to cancer formation" @default.
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