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• W2000333154 abstract "Dans une étude prospective menée de novembre 1996 à juillet 1997, les auteurs comparent l'ascitoculture à la procédure habituelle de culture du liquide d'ascite chez le cirrhotique. Parmi les 20 patients inclus dans l'étude (11 hommes, neuf femmes, âge moyen de 48,8 ans), 12 avaient une ISLA (60 %). Les caractéristiques associées à l'ISLA étaient la fièvre ou l'hypothermie, l'aspect trouble du liquide d'ascite, l'albuminémie et le taux de protides dans l'ascite ⩽ 10 g/l. Aucun germe n'avait été isolé avec la procédure bactériologique conventionnelle et 50 % des ascitocultures étaient positives ( p <0,05). Les germes identifiés (50 % de colibacilles, 50 % de staphylocoques) étaient sensibles à l'amoxycilline-acide clavulanique, aux céphalosporines et aux fluoroquinolones. En conclusion, l'ascitoculture était supérieure à la procédure bactériologique conventionnelle. Les bactéries isolées étaient sensibles aux antibiotiques habituellement utilisés dans le traitement et la prévention des ISLA. Objective – A prospective study was made to compare 2 methods of ascitic fluid culture. Patients and methods – All cirrhotic patients with ascites hospitalized between November 1996 and July 1997 were included to the study. Clinical data was obtained through standardized interviews and physical examination on inclusion. During the 24 hours following the patient's admission, we studied chemical, cytological, and bacteriological characteristics of ascitic fluid. The functional status of the liver was measured by blood sample analysis. Results – Twenty cirrhotic patients with ascites were enrolled in the study (11 men, nine women, average age 48.8 years). Twelve of them (60%) had spontaneous ascitic infection (SAI). The more frequent symptoms in the SAI group compared to controls were fever or hypothermia (91.7% vs 12.5%; p <0.001), cloudy ascitic fluid (66.7% vs 0%; p =0.003), moderately high albumin level in plasma (18.2 g/l vs 23.03 g/l; p =0.03), and ascitic fluid protein level ⩽ 10 g/l (91.7% vs 37.5%; p =0.02). We did not find any bacterium when using conventional ascitic fluid culture and 50% of ascitocultures were positives ( p <0.05). The bacteria identified (Escherichia: 50%; staphylococci: 50%) were not resistant for cephalosporins, amoxicillin-clavulanic acid, and fluoroquinolones. Conclusion – Bed-side ascitic fluid culture proved better than conventional ascitic fluid culture. The isolated bacteria were susceptible to commonly used antibiotics in the treatment and prevention of SAI." @default.
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• W2000333154 date "2002-04-01" @default.
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• W2000333154 title "Infection spontanée du liquide d'ascite chez le cirrhotique : évaluation prospective de deux procédures de culture du liquide d'ascite" @default.
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• W2000333154 doi "https://doi.org/10.1016/s0399-077x(02)00350-5" @default.
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