Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000334594> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2000334594 endingPage "388" @default.
- W2000334594 startingPage "384" @default.
- W2000334594 abstract "Metastatic involvement of the sentinel nodes (SN) is one of the main prognostic factors in cervical cancer which determines the disease management. The results of intra-operative SN examination would make it possible to triage patients in a one-step protocol. The studies carried out on the subject so far have, however, failed to demonstrate adequate accuracy of frozen section examination (FS) and, moreover, they only involved small cohorts.The study included 225 patients with cervical cancer FIGO IA2-IIB in whom at least one SN has been detected and intra-operatively processed. The prevalence of macrometastases, micrometastases and isolated tumour cells (ITC) in the SN was evaluated and the results of FS and final SN ultrastaging were compared.Metastatic involvement of the SN was detected by pathologic ultrastaging in 73 cases (32.4%); macrometastases, micrometastases and ITC were found in 48, 17 and 8 patients, respectively. Intra-operative SN assessment established the SN status correctly in as few as 41 cases (56.2%), or in 49 cases (63%) if ITC had been excluded. Final ultrastaging of intra-operatively negative SN confirmed macrometastases, micrometastases, and ITC in additional 8, 18 and 8 patients, respectively. The false negative rate of FS was higher in bigger tumours (>20 cm3) and in the presence of LVSI.Frozen section examination of SN is not sufficiently reliable; it has a high false negative rate mainly due to its limited ability to detect micrometastases. A possible solution would be a more detailed intra-operative pathologic processing or two-step surgical management." @default.
- W2000334594 created "2016-06-24" @default.
- W2000334594 creator A5003934490 @default.
- W2000334594 creator A5073232598 @default.
- W2000334594 creator A5078980245 @default.
- W2000334594 creator A5087027102 @default.
- W2000334594 date "2013-05-01" @default.
- W2000334594 modified "2023-10-12" @default.
- W2000334594 title "High false negative rate of frozen section examination of sentinel lymph nodes in patients with cervical cancer" @default.
- W2000334594 cites W1999117615 @default.
- W2000334594 cites W1999738237 @default.
- W2000334594 cites W2014589586 @default.
- W2000334594 cites W2027304733 @default.
- W2000334594 cites W2029156711 @default.
- W2000334594 cites W2034474620 @default.
- W2000334594 cites W2042855662 @default.
- W2000334594 cites W2076856445 @default.
- W2000334594 cites W2091468946 @default.
- W2000334594 cites W2096019467 @default.
- W2000334594 cites W2149655273 @default.
- W2000334594 cites W2160632716 @default.
- W2000334594 doi "https://doi.org/10.1016/j.ygyno.2013.02.001" @default.
- W2000334594 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23395889" @default.
- W2000334594 hasPublicationYear "2013" @default.
- W2000334594 type Work @default.
- W2000334594 sameAs 2000334594 @default.
- W2000334594 citedByCount "76" @default.
- W2000334594 countsByYear W20003345942014 @default.
- W2000334594 countsByYear W20003345942015 @default.
- W2000334594 countsByYear W20003345942016 @default.
- W2000334594 countsByYear W20003345942017 @default.
- W2000334594 countsByYear W20003345942018 @default.
- W2000334594 countsByYear W20003345942019 @default.
- W2000334594 countsByYear W20003345942020 @default.
- W2000334594 countsByYear W20003345942021 @default.
- W2000334594 countsByYear W20003345942022 @default.
- W2000334594 countsByYear W20003345942023 @default.
- W2000334594 crossrefType "journal-article" @default.
- W2000334594 hasAuthorship W2000334594A5003934490 @default.
- W2000334594 hasAuthorship W2000334594A5073232598 @default.
- W2000334594 hasAuthorship W2000334594A5078980245 @default.
- W2000334594 hasAuthorship W2000334594A5087027102 @default.
- W2000334594 hasConcept C121608353 @default.
- W2000334594 hasConcept C126322002 @default.
- W2000334594 hasConcept C126838900 @default.
- W2000334594 hasConcept C141071460 @default.
- W2000334594 hasConcept C142724271 @default.
- W2000334594 hasConcept C2778123414 @default.
- W2000334594 hasConcept C2778220009 @default.
- W2000334594 hasConcept C2779013556 @default.
- W2000334594 hasConcept C2779720271 @default.
- W2000334594 hasConcept C2909814700 @default.
- W2000334594 hasConcept C527108885 @default.
- W2000334594 hasConcept C71924100 @default.
- W2000334594 hasConcept C95798472 @default.
- W2000334594 hasConceptScore W2000334594C121608353 @default.
- W2000334594 hasConceptScore W2000334594C126322002 @default.
- W2000334594 hasConceptScore W2000334594C126838900 @default.
- W2000334594 hasConceptScore W2000334594C141071460 @default.
- W2000334594 hasConceptScore W2000334594C142724271 @default.
- W2000334594 hasConceptScore W2000334594C2778123414 @default.
- W2000334594 hasConceptScore W2000334594C2778220009 @default.
- W2000334594 hasConceptScore W2000334594C2779013556 @default.
- W2000334594 hasConceptScore W2000334594C2779720271 @default.
- W2000334594 hasConceptScore W2000334594C2909814700 @default.
- W2000334594 hasConceptScore W2000334594C527108885 @default.
- W2000334594 hasConceptScore W2000334594C71924100 @default.
- W2000334594 hasConceptScore W2000334594C95798472 @default.
- W2000334594 hasIssue "2" @default.
- W2000334594 hasLocation W20003345941 @default.
- W2000334594 hasLocation W20003345942 @default.
- W2000334594 hasOpenAccess W2000334594 @default.
- W2000334594 hasPrimaryLocation W20003345941 @default.
- W2000334594 hasRelatedWork W102334580 @default.
- W2000334594 hasRelatedWork W1999219372 @default.
- W2000334594 hasRelatedWork W2169217908 @default.
- W2000334594 hasRelatedWork W2364570576 @default.
- W2000334594 hasRelatedWork W2982319616 @default.
- W2000334594 hasRelatedWork W3030901629 @default.
- W2000334594 hasRelatedWork W3031238721 @default.
- W2000334594 hasRelatedWork W3036446242 @default.
- W2000334594 hasRelatedWork W78011566 @default.
- W2000334594 hasRelatedWork W3028931502 @default.
- W2000334594 hasVolume "129" @default.
- W2000334594 isParatext "false" @default.
- W2000334594 isRetracted "false" @default.
- W2000334594 magId "2000334594" @default.
- W2000334594 workType "article" @default.