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• W2000336715 abstract "The postnatal maturation of the human prefrontal cortex is associated with substantial increase of number of oligodendrocytes. Previously, we reported decreased numerical density of oligodendrocytes in the prefrontal cortex in schizophrenia and mood disorders. To gain further understanding of the role oligodendrocytes in pathogenesis of schizophrenia and mood disorders, we examined the effect of the age on the number of oligodendrocytes in the prefrontal cortex in schizophrenia, bipolar disorder, and major depressive disorder. We revealed the age-related increase in numerical density of oligodendrocytes in layer VI and adjacent white matter of BA10 and BA 9 in normal controls but not in schizophrenia, bipolar disorder, and major depressive disorder. The absence of normal increase in the number of oligodendrocytes in gray and white matter with age in schizophrenia and mood disorders suggests that age-related process of oligodendrocyte increase is dysregulated in schizophrenia and mood disorders." @default.
• W2000336715 created "2016-06-24" @default.
• W2000336715 creator A5002083037 @default.
• W2000336715 creator A5064996245 @default.
• W2000336715 date "2011-01-01" @default.
• W2000336715 modified "2023-09-29" @default.
• W2000336715 title "Age-Related Increase in the Number of Oligodendrocytes Is Dysregulated in Schizophrenia and Mood Disorders" @default.
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• W2000336715 doi "https://doi.org/10.1155/2011/174689" @default.
• W2000336715 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3420648" @default.

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