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- W2000337623 abstract "Abstract Four complementation groups have been found for phage S13 using two types of conditional lethal mutants, temperature-sensitive ( t ) and suppressible ( su ) mutants. Each complementation group contains both t and su mutants. Genetic crosses show that the mutants of each group are located in a separate region of the genetic map. Many group I t mutants are affected in their host range and adsorption properties and are therefore believed to lie in a genetic region determining the structure of the phage protein coat. su mutants of group IV are unable to lyse the restrictive host, E. coli C, while su mutants of groups I, II, and III lyse E. coli C completely. su mutants of all four groups produce little or no phage coat antigen in E. coli C. su mutants of groups I, II, and III are completely rescued by an su + phage in mixed infection of the restrictive host, but group IV su mutants are very poorly rescued. An su mutant has been isolated which appears to be an O 0 or polar mutant, since it is defective in the functions of both groups III and IV, yet does not seem to be a double mutant. Mapping experiments show that map distances are roughly additive for groups I, III, and IV." @default.
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- W2000337623 date "1965-02-01" @default.
- W2000337623 modified "2023-09-23" @default.
- W2000337623 title "Complementation groups in phage S13" @default.
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- W2000337623 doi "https://doi.org/10.1016/0042-6822(65)90208-4" @default.
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