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- W2000340145 abstract "We analyzed the lymphocyte function of MCLS in pokeweed mitogen-induced immunoglobulin production. T cell suppressor activity was activated in the acute phase adn normalized in convalescence. T cells showing suppressor activity in this system were identified to be Tg cells, and they seemed to be activated as suppressor by a certain factor in the serum. the sera of patients whose T cells showed suppressor activity could induce the suppresoor activity of normal control Tg cells. The suppressor inducing factor in sera is likely to be circulating immune complexes, since Tg cells usually show suppressor activity when they interact with immune complexes. The induction of the suppressor activity of Tg cells by immune complexes may provide a kind of negative feedback suppression mechanism feedback mechanism on the antibody formation and it may be related to the self-limiting characteristics of MCLS. MCLS is different from collagen diseases such as rheumatoid arthritis in that Tg cells do not usually work as suppressor cells in the later diseases." @default.
- W2000340145 created "2016-06-24" @default.
- W2000340145 creator A5037127463 @default.
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- W2000340145 date "1983-06-01" @default.
- W2000340145 modified "2023-09-25" @default.
- W2000340145 title "An Immunological Study on Mucocutaneous Lymph Node Syndrome: Activation of TgSuppressor Cells" @default.
- W2000340145 doi "https://doi.org/10.1111/j.1442-200x.1983.tb01686.x" @default.
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