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- W2000341138 abstract "The involvement of the β3-adrenoceptor in the antidepressant-like effects of the β3-adrenoceptor-agonist amibegron is addressed in the chronic mild stress, using adrenergic β3-receptor knockout (Adrb3tm1Lowl) mice. Amibegron (3 mg/kg/day, i.p., 33 days), attenuated the physical alteration due to the application of repeated stress in wild-type littermates, but not in knockout mice. This result suggests that the β3-adrenoceptor plays a predominant role in mediating antidepressant-like actions of amibegron." @default.
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- W2000341138 date "2010-01-01" @default.
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- W2000341138 title "Implication of β3-adrenoceptors in the antidepressant-like effects of amibegron using Adrb3 knockout mice in the chronic mild stress" @default.
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- W2000341138 doi "https://doi.org/10.1016/j.bbr.2009.09.003" @default.
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