FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000341490> ?p ?o ?g. }

• W2000341490 endingPage "97" @default.
• W2000341490 startingPage "91" @default.
• W2000341490 abstract "The soluble form of the transmembrane glycoprotein CD23 corresponding to the low-affinity receptor for the immunoglobulin E (sCD23) is found in the serum of patients with chronic lymphocytic leukemia (CLL). In this disease, an increase in sCD23 level is predictive of poor prognosis at diagnosis as well as during clinical outcome. Quantification of sCD23 is classically performed by enzyme-linked immunosorbent assay (ELISA), a method not routinely used in hematology laboratories. Our aim was to apply cytometric bead array (CBA) technology to measure sCD23 levels. We tested 420 serum samples, 360 from patients and 60 from healthy volunteers. We selected three pairs of monoclonal antibodies recognizing the CD23 molecule that were tested in various conditions of temperature, centrifugation, washing, or chemical supplementation. Satisfactory performances in terms of repeatability (CV: 5%) and reproducibility (CV: 6%) were obtained with the selected pair of antibodies, with a threshold of positivity at 6 ng/mL. CBA and ELISA techniques were correlated with a Spearman coefficient at 0.99. The reproducibility and reliability of the sCD23 CBA assay were confirmed, with a Spearman coefficient at 0.99 in a series of 23 CLL patients and 13 controls tested in two laboratories equipped with different cytometers and using different lots of CBA reagents. Data obtained with serum and plasma samples were correlated with a Spearman coefficient at 0.99. Our study validates a simple method that allows the clinicians to benefit from an indicator of prognosis at the diagnosis as well as a marker of the evolution of CLL disease." @default.
• W2000341490 created "2016-06-24" @default.
• W2000341490 creator A5000418549 @default.
• W2000341490 creator A5007611864 @default.
• W2000341490 creator A5051576311 @default.
• W2000341490 creator A5064884355 @default.
• W2000341490 creator A5074912438 @default.
• W2000341490 date "2013-10-21" @default.
• W2000341490 modified "2023-10-17" @default.
• W2000341490 title "Soluble CD23 measurement by CBA: A convenient and reliable quantification method in chronic lymphocytic leukemia" @default.
• W2000341490 cites W130820818 @default.
• W2000341490 cites W143899559 @default.
• W2000341490 cites W1855218521 @default.
• W2000341490 cites W1957256977 @default.
• W2000341490 cites W1965111451 @default.
• W2000341490 cites W1970296317 @default.
• W2000341490 cites W1987657678 @default.
• W2000341490 cites W1991696977 @default.
• W2000341490 cites W2001010891 @default.
• W2000341490 cites W2022054497 @default.
• W2000341490 cites W2053085787 @default.
• W2000341490 cites W2082620902 @default.
• W2000341490 cites W2087289805 @default.
• W2000341490 cites W2088952848 @default.
• W2000341490 cites W2142099365 @default.
• W2000341490 cites W2148766690 @default.
• W2000341490 cites W2149858385 @default.
• W2000341490 cites W2163460786 @default.
• W2000341490 cites W2397727880 @default.
• W2000341490 cites W343303420 @default.
• W2000341490 cites W95166418 @default.
• W2000341490 cites W97246880 @default.
• W2000341490 doi "https://doi.org/10.1002/cyto.b.21135" @default.
• W2000341490 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24150841" @default.
• W2000341490 hasPublicationYear "2013" @default.
• W2000341490 type Work @default.
• W2000341490 sameAs 2000341490 @default.
• W2000341490 citedByCount "1" @default.
• W2000341490 countsByYear W20003414902014 @default.
• W2000341490 crossrefType "journal-article" @default.
• W2000341490 hasAuthorship W2000341490A5000418549 @default.
• W2000341490 hasAuthorship W2000341490A5007611864 @default.
• W2000341490 hasAuthorship W2000341490A5051576311 @default.
• W2000341490 hasAuthorship W2000341490A5064884355 @default.
• W2000341490 hasAuthorship W2000341490A5074912438 @default.
• W2000341490 hasConcept C126322002 @default.
• W2000341490 hasConcept C141105273 @default.
• W2000341490 hasConcept C154020017 @default.
• W2000341490 hasConcept C159654299 @default.
• W2000341490 hasConcept C185592680 @default.
• W2000341490 hasConcept C203014093 @default.
• W2000341490 hasConcept C2777938653 @default.
• W2000341490 hasConcept C2778461978 @default.
• W2000341490 hasConcept C34814297 @default.
• W2000341490 hasConcept C43617362 @default.
• W2000341490 hasConcept C71924100 @default.
• W2000341490 hasConcept C89838059 @default.
• W2000341490 hasConcept C9893847 @default.
• W2000341490 hasConceptScore W2000341490C126322002 @default.
• W2000341490 hasConceptScore W2000341490C141105273 @default.
• W2000341490 hasConceptScore W2000341490C154020017 @default.
• W2000341490 hasConceptScore W2000341490C159654299 @default.
• W2000341490 hasConceptScore W2000341490C185592680 @default.
• W2000341490 hasConceptScore W2000341490C203014093 @default.
• W2000341490 hasConceptScore W2000341490C2777938653 @default.
• W2000341490 hasConceptScore W2000341490C2778461978 @default.
• W2000341490 hasConceptScore W2000341490C34814297 @default.
• W2000341490 hasConceptScore W2000341490C43617362 @default.
• W2000341490 hasConceptScore W2000341490C71924100 @default.
• W2000341490 hasConceptScore W2000341490C89838059 @default.
• W2000341490 hasConceptScore W2000341490C9893847 @default.
• W2000341490 hasIssue "2" @default.
• W2000341490 hasLocation W20003414901 @default.
• W2000341490 hasLocation W20003414902 @default.
• W2000341490 hasOpenAccess W2000341490 @default.
• W2000341490 hasPrimaryLocation W20003414901 @default.
• W2000341490 hasRelatedWork W1987571240 @default.
• W2000341490 hasRelatedWork W2080526977 @default.
• W2000341490 hasRelatedWork W2122614767 @default.
• W2000341490 hasRelatedWork W2167894338 @default.
• W2000341490 hasRelatedWork W2171058574 @default.
• W2000341490 hasRelatedWork W2202042085 @default.
• W2000341490 hasRelatedWork W2209593772 @default.
• W2000341490 hasRelatedWork W2947399876 @default.
• W2000341490 hasRelatedWork W2990766896 @default.
• W2000341490 hasRelatedWork W4361287320 @default.
• W2000341490 hasVolume "86" @default.
• W2000341490 isParatext "false" @default.
• W2000341490 isRetracted "false" @default.
• W2000341490 magId "2000341490" @default.
• W2000341490 workType "article" @default.