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- W2000347710 abstract "Tests of cathartics on the usual types of laboratory animals were reviewed. The unsatisfactory results obtained with the emodin type of drugs led to the development of a satisfactory method of bioassay on rats. The DD50 was determined by administration to a significant number of animals at several dosage levels; the consistency of the expressed fecal matter was determined eighteen hours later. Suitable standards were developed for comparable bioassays of several cathartics of the emodin type. The precision of these studies was about 15 per cent." @default.
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- W2000347710 date "1952-10-01" @default.
- W2000347710 modified "2023-09-26" @default.
- W2000347710 title "Bioassay of Cathartics. I. Emodin Type" @default.
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- W2000347710 doi "https://doi.org/10.1002/jps.3030411013" @default.
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